HitPredict

Interactor 1: CCL28 (Q9NRJ3)
C-C motif chemokine 28 (Mucosae-associated epithelial chemokine) (MEC) (Protein CCK1) (Small-inducible cytokine A28)
Gene: CCL28

Interactor 2: CCL26 (Q9Y258)
C-C motif chemokine 26 (CC chemokine IMAC) (Eotaxin-3) (Macrophage inflammatory protein 4-alpha) (MIP-4-alpha) (Small-inducible cytokine A26) (Thymic stroma chemokine-1) (TSC-1)
Gene: CCL26

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.692

Property	Details
Experiments	28381538
Identification Methods	pull down, filter binding
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	IL8~IL8
Common GO terms	GO:0005615 - extracellular space GO:0006935 - chemotaxis GO:0006954 - inflammatory response GO:0008009 - chemokine activity GO:0061844 - antimicrobial humoral immune response mediated by antimicrobial peptide
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 127 Hs			1 94
+	Hs
		1405934 CCL28_HUMAN (1-127): 1.93e-68: 203: 100.00		CCL13_HUMAN (2-91): 2.05e-31: 107: 33.70
+	Hs
		1365147 CCL28_HUMAN (1-127): 1.93e-68: 203: 100.00		CCL17_HUMAN (1-89): 5.67e-28: 98.9: 29.21
+	Hs
		562909 CCL28_HUMAN (1-127): 1.93e-68: 203: 100.00		CCL5_HUMAN (14-90): 4e-25: 91.6: 37.66
+	Hs
		906853 CCL28_HUMAN (1-127): 1.93e-68: 203: 100.00		CCL11_HUMAN (16-92): 6.21e-25: 91.2: 34.62
+	Hs
		1448611 CCL28_HUMAN (1-127): 1.93e-68: 203: 100.00		XCL2_HUMAN (6-92): 2.15e-21: 82.7: 28.74
+	Hs
		869323 CCL28_HUMAN (1-127): 1.93e-68: 203: 100.00		XCL1_HUMAN (6-92): 5.61e-21: 81.5: 29.89
+	Hs
		141768 CCL28_HUMAN (1-127): 1.93e-68: 203: 100.00		CCL21_HUMAN (25-91): 5.28e-17: 71.9: 28.17
+	Hs
		562913 CCL27_HUMAN (23-94): 1.8e-37: 124: 39.73		CCL5_HUMAN (14-90): 4e-25: 91.6: 37.66
+	Hs
		906855 CCL27_HUMAN (23-94): 1.8e-37: 124: 39.73		CCL11_HUMAN (16-92): 6.21e-25: 91.2: 34.62