Protein: ACE
Angiotensin-converting enzyme (ACE) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form]

Gene: ACE
Organism: Homo sapiens
Interactions: 20
UniProt ID: P12821

Gene Ontology (top 5):
GO:0001666 - response to hypoxia
GO:0001822 - kidney development
GO:0001974 - blood vessel remodeling
GO:0002003 - angiotensin maturation
GO:0002019 - regulation of renal output by angiotensin

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

344361

ANGT
Angiotensinogen

3

4

Small-scale

0.646

High

521666

BKRB2
B2 bradykinin receptor

1

2

Small-scale

0.561

High

521673

TX101
Testis-expressed protein 101

1

1

High-throughput

0.536

High

521667

MYH9
Myosin-9

1

3

Small-scale

0.527

High

449167

LEG1
Galectin-1

1

0

High-throughput

0.513

High

521669

CSK21
Casein kinase II subunit alpha

1

0

Small-scale

0.505

High

403753

ITB1
Integrin beta-1

1

5

Small-scale

0.479

High

521663

ITB5
Integrin beta-5

1

3

Small-scale

0.479

High

521668

ACTB
Actin, cytoplasmic 1

1

1

Small-scale

0.479

High

521670

EWS
RNA-binding protein EWS

1

2

High-throughput

0.479

High

521675

HOOK1
Protein Hook homolog 1

1

4

High-throughput

0.479

High

329300

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.458

High

521672

HIF1A
Hypoxia-inducible factor 1-alpha

1

0

Small-scale

0.458

High

359611

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

8

High-throughput

0.437

High

521671

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

1

High-throughput

0.437

High

521676

NINL
Ninein-like protein

1

7

High-throughput

0.437

High

521664

CD3Z
T-cell surface glycoprotein CD3 zeta chain

1

0

High-throughput

0.426

High

521665

DDX6
Probable ATP-dependent RNA helicase DDX6

1

4

Small-scale

0.407

High

128965

PLK4
Serine/threonine-protein kinase PLK4

1

0

High-throughput

0.279

Low

521674

METL9
Protein-L-histidine N-pros-methyltransferase

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024