Protein: CCL21
C-C motif chemokine 21 (6Ckine) (Beta-chemokine exodus-2) (Secondary lymphoid-tissue chemokine) (SLC) (Small-inducible cytokine A21)

Gene: CCL21
Organism: Homo sapiens
Interactions: 40
UniProt ID: O00585

Gene Ontology (top 5):
GO:0001768 - establishment of T cell polarity
GO:0001771 - immunological synapse formation
GO:0001954 - positive regulation of cell-matrix adhesion
GO:0002407 - dendritic cell chemotaxis
GO:0002606 - positive regulation of dendritic cell antigen processing and presentation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

141747

CCR7
C-C chemokine receptor type 7

3

20

Small-scale

0.827

High

141767

ACKR4
Atypical chemokine receptor 4

1

20

Small-scale

0.724

High

141739

PLF4
Platelet factor 4

1

20

High-throughput

0.716

High

141743

CCL5
C-C motif chemokine 5

1

18

High-throughput

0.716

High

141749

SDF1
Stromal cell-derived factor 1

1

8

High-throughput

0.716

High

141765

CCL17
C-C motif chemokine 17

1

18

High-throughput

0.716

High

124861

CCL24
C-C motif chemokine 24

1

18

High-throughput

0.692

High

141734

CXL11
C-X-C motif chemokine 11

1

20

High-throughput

0.692

High

141735

CXL14
C-X-C motif chemokine 14

1

6

High-throughput

0.692

High

141738

CXCL7
Platelet basic protein

1

20

High-throughput

0.692

High

141740

CXL10
C-X-C motif chemokine 10

1

20

High-throughput

0.692

High

141742

PF4V
Platelet factor 4 variant

1

20

High-throughput

0.692

High

141745

CXCL2
C-X-C motif chemokine 2

1

20

High-throughput

0.692

High

141748

XCL1
Lymphotactin

1

18

High-throughput

0.692

High

141751

CCL23
C-C motif chemokine 23

1

18

High-throughput

0.692

High

141753

CXCL9
C-X-C motif chemokine 9

1

20

High-throughput

0.692

High

141766

CCL13
C-C motif chemokine 13

1

19

High-throughput

0.692

High

141768

CCL28
C-C motif chemokine 28

1

9

High-throughput

0.692

High

141770

XCL2
Cytokine SCM-1 beta

1

18

High-throughput

0.692

High

141772

CCL26
C-C motif chemokine 26

1

18

High-throughput

0.692

High

141744

CSPG2
Versican core protein

1

10

Small-scale

0.647

High

141755

TRIP6
Thyroid receptor-interacting protein 6

2

1

High-throughput

0.628

High

141750

CLH2
Clathrin heavy chain 2

2

1

High-throughput

0.574

High

141758

KLH26
Kelch-like protein 26

2

2

High-throughput

0.574

High

141759

TTMP
TPA-induced transmembrane protein

2

1

High-throughput

0.553

High

141761

OTP
Homeobox protein orthopedia

2

1

High-throughput

0.553

High

141756

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

2

1

High-throughput

0.550

High

141763

CXL17
C-X-C motif chemokine 17

1

10

High-throughput

0.536

High

141771

ASC
Apoptosis-associated speck-like protein containing a CARD

1

0

High-throughput

0.513

High

141752

TSG6
Tumor necrosis factor-inducible gene 6 protein

1

15

Small-scale

0.501

High

141760

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.501

High

141769

UBQL4
Ubiquilin-4

1

5

High-throughput

0.494

High

141757

KLH22
Kelch-like protein 22

1

2

High-throughput

0.489

High

141741

CATD
Cathepsin D

1

3

Small-scale

0.445

High

141762

TM107
Transmembrane protein 107

2

0

High-throughput

0.316

High

141737

HBAZ
Hemoglobin subunit zeta

1

0

High-throughput

0.279

Low

141746

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

0

High-throughput

0.269

Low

141754

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

0

High-throughput

0.269

Low

141764

JPH3
Junctophilin-3

1

0

High-throughput

0.268

Low

141736

AATM
Aspartate aminotransferase, mitochondrial

1

0

High-throughput

0.265

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025