Interactor 1: TRM1 (Q9NXH9)
tRNA (guanine(26)-N(2))-dimethyltransferase (EC 2.1.1.216) (tRNA 2,2-dimethylguanosine-26 methyltransferase) (tRNA methyltransferase 1) (hTRM1) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase)
Gene: TRMT1

Interactor 2: TRM1 (Q9NXH9)
tRNA (guanine(26)-N(2))-dimethyltransferase (EC 2.1.1.216) (tRNA 2,2-dimethylguanosine-26 methyltransferase) (tRNA methyltransferase 1) (hTRM1) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase)
Gene: TRMT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 31839598
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains TRM~TRM, zf-CCCH~zf-CCCH
Common GO terms GO:0000049 - tRNA binding
GO:0002940 - tRNA N2-guanine methylation
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 5 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 659
Hs

1 659
+ Sc
+ Hs

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Last updated: 11Aug2025