Protein: TRM1
tRNA (guanine(26)-N(2))-dimethyltransferase, mitochondrial (EC 2.1.1.216) (tRNA 2,2-dimethylguanosine-26 methyltransferase) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase)

Gene: TRM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 86
UniProt ID: P15565

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0002940 - tRNA N2-guanine methylation
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0005637 - nuclear inner membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

584881

TRM1
tRNA

1

2

High-throughput

0.665

High

584936

GCN5
Histone acetyltransferase GCN5

1

3

High-throughput

0.536

High

584893

SBA1
Co-chaperone protein SBA1

1

0

Small-scale

0.504

High

441020

KAPA
cAMP-dependent protein kinase type 1

1

2

High-throughput

0.501

High

584883

FUS3
Mitogen-activated protein kinase FUS3

1

2

High-throughput

0.501

High

584914

AURK
Aurora kinase

1

3

High-throughput

0.501

High

584917

RSP5
E3 ubiquitin-protein ligase RSP5

1

2

Small-scale

0.501

High

584919

TPA1
Prolyl 3,4-dihydroxylase TPA1

1

0

High-throughput

0.493

High

584945

SMT3
Ubiquitin-like protein SMT3

1

1

High-throughput

0.481

High

448629

SNF1
Carbon catabolite-derepressing protein kinase

1

0

High-throughput

0.480

High

584884

PHO85
Cyclin-dependent protein kinase PHO85

1

0

High-throughput

0.480

High

584899

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

0

High-throughput

0.480

High

584882

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.479

High

584885

PSA7
Probable proteasome subunit alpha type-7

1

1

High-throughput

0.479

High

584886

PSA1
Proteasome subunit alpha type-1

1

1

High-throughput

0.479

High

584894

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

584897

HS104
Heat shock protein 104

1

3

High-throughput

0.479

High

584898

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

584900

HOG1
Mitogen-activated protein kinase HOG1

1

2

High-throughput

0.479

High

584935

TOM1
E3 ubiquitin-protein ligase TOM1

1

2

High-throughput

0.479

High

584937

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

1

High-throughput

0.479

High

584941

IMH1
Golgin IMH1

1

1

High-throughput

0.470

High

434783

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

514424

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

554548

RM02
Large ribosomal subunit protein bL27m

1

0

High-throughput

0.458

High

584887

PSA2
Proteasome subunit alpha type-2

1

0

High-throughput

0.458

High

584888

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

584895

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

584896

PSB7
Proteasome subunit beta type-7

1

0

High-throughput

0.458

High

584921

PSA6
Proteasome subunit alpha type-6

1

0

High-throughput

0.458

High

584922

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

584924

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

584925

BLM10
Proteasome activator BLM10

1

0

High-throughput

0.458

High

584929

NSA1
Ribosome biogenesis protein NSA1

1

0

High-throughput

0.458

High

584930

TR112
Multifunctional methyltransferase subunit TRM112

1

0

Small-scale

0.458

High

584932

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.458

High

584938

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

584940

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

584943

SGO1
Shugoshin

1

0

High-throughput

0.458

High

584947

RUVB2
RuvB-like protein 2

1

0

High-throughput

0.458

High

522943

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

543696

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

584901

ZUO1
Zuotin

1

1

High-throughput

0.445

High

584902

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

584905

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.445

High

584907

SPT7
SAGA complex subunit SPT7

1

2

High-throughput

0.445

High

584912

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.445

High

584920

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

584927

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

1

High-throughput

0.445

High

584890

GBP2
Serine/arginine

1

0

High-throughput

0.438

High

584923

GST1
Glutathione S-transferase 1

1

0

High-throughput

0.438

High

584942

MLH2
DNA mismatch repair protein MLH2

1

0

High-throughput

0.438

High

409905

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.437

High

433412

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.437

High

435739

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.437

High

504010

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

512227

RS6A
Small ribosomal subunit protein eS6A

1

2

High-throughput

0.437

High

584913

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.426

High

584915

CAJ1
Protein CAJ1

1

0

High-throughput

0.426

High

584928

SPT20
SAGA complex subunit SPT20

1

0

High-throughput

0.426

High

584934

ADA2
SAGA complex subunit ADA2

1

0

High-throughput

0.426

High

584939

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

0

High-throughput

0.426

High

584944

HFI1
SAGA complex subunit HFI1

1

0

High-throughput

0.426

High

584926

ENT3
Epsin-3

1

0

Small-scale

0.261

Low

149554

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.249

Low

383488

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

441673

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

454841

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

502816

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

512785

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

584889

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.249

Low

584891

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low

584892

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

584903

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

584904

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

584906

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

584908

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

584909

ATG8
Autophagy-related protein 8

1

0

High-throughput

0.249

Low

584910

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

584911

YHI0
Putative proline--tRNA ligase YHR020W

1

0

High-throughput

0.249

Low

584916

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

584931

GIS2
Zinc finger protein GIS2

1

0

High-throughput

0.249

Low

584933

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

584946

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.249

Low

584918

GTT3
Glutathione transferase 3

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025