HitPredict

Interactor 1: TOR1 (O14356)
Serine/threonine-protein kinase tor1 (EC 2.7.11.1) (Phosphatidylinositol kinase homolog tor1) (Target of rapamycin kinase 1)
Gene: TOR1

Interactor 2: TTI1 (O94600)
TEL2-interacting protein 1
Gene: TTI1

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	18076573, 34686329
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 2335 Sp			1 1098
+	Sp
		293733 TOR2_SCHPO (1-2335): 0: 1803: 51.84		TTI1_SCHPO (1-1098): 0: 1516: 100.00
+	Sc
		715177 TOR1_YEAST (2-2335): 0: 1721: 43.40		TTI1_YEAST (49-979): 0: 914: 19.60
+	Dm
		1366743 TOR_DROME (2-2335): 0: 1596: 38.57		Q9VH80_DROME (142-928): 0: 784: 15.82
+	Sp
		293730 TRA1_SCHPO (3-2334): 0: 842: 13.79		TTI1_SCHPO (1-1098): 0: 1516: 100.00
+	Sp
		293728 YAMB_SCHPO (72-2334): 0: 783: 13.28		TTI1_SCHPO (1-1098): 0: 1516: 100.00
+	Sp
		293727 RAD3_SCHPO (356-2335): 0: 741: 15.18		TTI1_SCHPO (1-1098): 0: 1516: 100.00
+	Sp
		251726 ATM_SCHPO (1065-2334): 4.58e-163: 565: 17.89		TTI1_SCHPO (1-1098): 0: 1516: 100.00
+	Hs
		195892 MTOR_HUMAN (2-2335): 0: 1603: 39.63		TTI1_HUMAN (50-919): 4.64e-121: 400: 18.24
+	At
		96186 TOR_ARATH (13-2335): 0: 1660: 38.74		F4IDJ4_ARATH (569-927): 1.72e-88: 313: 16.17
+	Sc
		732564 TRA1_YEAST (410-2335): 0: 785: 14.27		TTI1_YEAST (49-979): 0: 914: 19.60
+	Dm
		1211951 TRA1_DROME (319-2334): 0: 774: 13.97		Q9VH80_DROME (142-928): 0: 784: 15.82
+	Hs
		195905 ATM_HUMAN (308-2334): 0: 939: 15.79		TTI1_HUMAN (50-919): 4.64e-121: 400: 18.24
+	Hs
		195907 ATR_HUMAN (24-2334): 0: 918: 15.10		TTI1_HUMAN (50-919): 4.64e-121: 400: 18.24
+	Hs
		195955 TRRAP_HUMAN (319-2334): 0: 838: 14.31		TTI1_HUMAN (50-919): 4.64e-121: 400: 18.24
+	Hs
		195901 PRKDC_HUMAN (4-2334): 0: 762: 14.96		TTI1_HUMAN (50-919): 4.64e-121: 400: 18.24
+	Hs
		195935 SMG1_HUMAN (2231-2334): 4.99e-17: 90.7: 23.08		TTI1_HUMAN (50-919): 4.64e-121: 400: 18.24