Interactor 1: TR112 (Q9UI30)
Multifunctional methyltransferase subunit TRM112-like protein (tRNA methyltransferase 112 homolog)
Gene: TRMT112

Interactor 2: HEMK2 (Q9Y5N5)
Methyltransferase HEMK2 (HemK methyltransferase family member 2) (M.HsaHemK2P) (Lysine N-methyltransferase 9) (EC 2.1.1.-) (Methylarsonite methyltransferase N6AMT1) (EC 2.1.1.-) (Methyltransferase N6AMT1) (Protein N(5)-glutamine methyltransferase) (EC 2.1.1.-)
Gene: HEMK2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.834

The method score is based on:

Property Details
Experiments 34948388, 25851604, 18539146
Identification Methods anti tag coimmunoprecipitation, pull down
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains MTS~Trm112p
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0008276 - protein methyltransferase activity
GO:0018364 - peptidyl-glutamine methylation
GO:0032991 - protein-containing complex
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 125
Hs

1 214
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025