Interactor 1: TR112 (P53738)
Multifunctional methyltransferase subunit TRM112 (eRF1 methyltransferase subunit TRM112) (eRF1 MTase subunit TRM112) (tRNA methyltransferase 112)
Gene: TRM112

Interactor 2: MTQ2 (Q03920)
eRF1 methyltransferase catalytic subunit MTQ2 (eRF1 MTase catalytic subunit MTQ2) (EC 2.1.1.297) (N(5)-glutamine methyltransferase MTQ2)
Gene: MTQ2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.970

The method score is based on:

Property Details
Experiments 11283351, 10655498, 11805826, 33166396, 37968396, 16429126, 18719252, 20400505, 22493060
Identification Methods two hybrid pooling approach, two hybrid, tandem affinity purification, affinity chromatography technology
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains MTS~Trm112p
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005840 - ribosome
GO:0035657 - eRF1 methyltransferase complex
GO:0042273 - ribosomal large subunit biogenesis
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 135
Sc

1 221
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025