HitPredict

Interactor 1: PCDA6 (Q9UN73)
Protocadherin alpha-6 (PCDH-alpha-6)
Gene: PCDHA6

Interactor 2: PCDGH (Q9Y5G0)
Protocadherin gamma-B5 (PCDH-gamma-B5)
Gene: PCDHGB5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Cadherin~Cadherin, Cadherin~Cadherin_2
Common GO terms	GO:0005509 - calcium ion binding GO:0005886 - plasma membrane GO:0007155 - cell adhesion GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules GO:0007399 - nervous system development
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 950 Hs			1 923
+	Hs
		1491609 PCDA8_HUMAN (1-950): 0: 1120: 90.53		PCDGH_HUMAN (1-908): 0: 1183: 100.00
+	Hs
		1462174 PCDA6_HUMAN (1-950): 0: 1128: 100.00		PCDGG_HUMAN (1-908): 0: 1154: 85.39
+	Hs
		1462187 PCDA8_HUMAN (1-950): 0: 1120: 90.53		PCDGG_HUMAN (1-908): 0: 1154: 85.39
+	Hs
		1462200 PCDA6_HUMAN (1-950): 0: 1128: 100.00		PCDC2_HUMAN (27-896): 0: 973: 37.88
+	Hs
		1491559 PCDA8_HUMAN (1-950): 0: 1120: 90.53		PCDB2_HUMAN (1-784): 0: 942: 43.94
+	Hs
		1462149 PCDA8_HUMAN (1-950): 0: 1120: 90.53		PCDB8_HUMAN (35-764): 0: 614: 46.79
+	Hs
		1491567 PCDA8_HUMAN (1-950): 0: 1120: 90.53		PCDBE_HUMAN (6-764): 0: 606: 45.55
+	Hs
		1491584 PCDA8_HUMAN (1-950): 0: 1120: 90.53		PCDBB_HUMAN (16-764): 0: 603: 45.62
+	Hs
		1462160 PCDA8_HUMAN (1-950): 0: 1120: 90.53		PCDBA_HUMAN (7-764): 0: 583: 46.29
+	Hs
		1462198 PCDA6_HUMAN (1-950): 0: 1128: 100.00		PCDA3_HUMAN (2-438): 4.4e-99: 333: 25.65
+	Hs
		1462197 PCDA6_HUMAN (1-950): 0: 1128: 100.00		PCDA8_HUMAN (2-438): 1.44e-97: 329: 26.45
+	Hs
		1462205 PCDA8_HUMAN (1-950): 0: 1120: 90.53		PCDA4_HUMAN (2-438): 1.36e-99: 334: 26.51
+	Hs
		1462192 PCDA8_HUMAN (1-950): 0: 1120: 90.53		PCDA7_HUMAN (2-438): 2.9e-98: 331: 26.51
+	Hs
		1462173 PCDA8_HUMAN (1-950): 0: 1120: 90.53		PCDGK_HUMAN (2-439): 1.4e-93: 318: 26.20
+	Hs
		1491591 PCDA8_HUMAN (1-950): 0: 1120: 90.53		PCDGL_HUMAN (2-439): 1.77e-91: 312: 25.27
+	Hs
		1491538 PCDA8_HUMAN (1-950): 0: 1120: 90.53		PCDB5_HUMAN (1-335): 7.94e-59: 217: 23.03
+	Hs
		1462196 PCDA6_HUMAN (1-950): 0: 1128: 100.00		PCDGD_HUMAN (1-234): 1.37e-33: 141: 20.55
+	Hs
		1462199 PCDA6_HUMAN (1-950): 0: 1128: 100.00		PCDAA_HUMAN (2-233): 9.73e-32: 135: 20.24
+	Hs
		1462217 PCDA8_HUMAN (1-950): 0: 1120: 90.53		PCDAC_HUMAN (2-267): 8.8e-34: 142: 18.82