HitPredict - High confidence protein-protein interactions

Interactor 1: SHOC2 (Q9UQ13)
Leucine-rich repeat protein SHOC-2 (Protein soc-2 homolog) (Protein sur-8 homolog)
Gene: SHOC2

Interactor 2: SHOC2 (Q9UQ13)
Leucine-rich repeat protein SHOC-2 (Protein soc-2 homolog) (Protein sur-8 homolog)
Gene: SHOC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31980649
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LRR_8~LRR_8
Common GO terms	GO:0000164 - protein phosphatase type 1 complex GO:0005225 - volume-sensitive anion channel activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 15 others more... GO:0005829 - cytosol GO:0008157 - protein phosphatase 1 binding GO:0008543 - fibroblast growth factor receptor signaling pathway GO:0010976 - positive regulation of neuron projection development GO:0019888 - protein phosphatase regulator activity GO:0019903 - protein phosphatase binding GO:0035556 - intracellular signal transduction GO:0038180 - nerve growth factor signaling pathway GO:0043408 - regulation of MAPK cascade GO:0045665 - negative regulation of neuron differentiation GO:0045666 - positive regulation of neuron differentiation GO:0046579 - positive regulation of Ras protein signal transduction GO:0071378 - cellular response to growth hormone stimulus GO:0140361 - cyclic-GMP-AMP transmembrane import across plasma membrane GO:2000178 - negative regulation of neural precursor cell proliferation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1	582
Hs

1	582

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Last updated: 11Aug2025