HitPredict

Interactor 1: ISLR (O14498)
Immunoglobulin superfamily containing leucine-rich repeat protein
Gene: ISLR

Interactor 2: LRC40 (Q9H9A6)
Leucine-rich repeat-containing protein 40
Gene: LRRC40

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.80	0.705

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LRR_8~LRR_8
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 428 Hs			1 602
+	Dm
		1360610 Q9V9V6_DROME (4-346): 1.59e-78: 261: 19.68		TOLL6_DROME (127-557): 3.52e-12: 71.6: 25.88
+	Hs
		146395 ISLR_HUMAN (18-404): 3.69e-66: 219: 100.00		LRRC1_HUMAN (41-220): 2.84e-14: 77.8: 31.11
+	Mm
		1193434 LRC4C_MOUSE (3-409): 4.24e-56: 197: 17.66		ERBIN_MOUSE (198-578): 7.52e-14: 77: 24.48
+	Mm
		1193424 LRC4C_MOUSE (3-409): 4.24e-56: 197: 17.66		LRRC7_MOUSE (401-602): 7.57e-09: 60.8: 25.45
+	Hs
		1050047 LGR4_HUMAN (19-176): 4.6e-21: 97.8: 37.34		SCRIB_HUMAN (364-601): 3.28e-37: 150: 21.85
+	Hs
		1050029 LRIG1_HUMAN (33-317): 1.32e-20: 96.8: 17.63		SCRIB_HUMAN (364-601): 3.28e-37: 150: 21.85
+	At
		1323503 IMK2_ARATH (51-321): 4.73e-25: 109: 14.02		TDR_ARATH (6-279): 9.97e-31: 130: 18.31
+	At
		186954 BRI1_ARATH (11-320): 3.49e-18: 89.1: 13.03		BAME1_ARATH (14-265): 2.92e-34: 141: 21.62
+	At
		84587 BRI1_ARATH (11-320): 3.49e-18: 89.1: 13.03		RGI3_ARATH (1-256): 1.6e-32: 135: 22.26
+	Gm
		1341216 CLV1B_SOYBN (51-321): 1.31e-19: 93.8: 14.75		CLV1B_SOYBN (21-254): 8.64e-30: 127: 20.25
+	Hs
		1294956 LRIG1_HUMAN (33-317): 1.32e-20: 96.8: 17.63		LRC40_HUMAN (1-256): 1.44e-25: 113: 21.45
+	At
		1325020 PXL1_ARATH (30-317): 4.35e-23: 104: 15.02		PXL1_ARATH (4-185): 2.04e-21: 101: 16.11
+	At
		85399 BRI1_ARATH (11-320): 3.49e-18: 89.1: 13.03		HSL2_ARATH (354-601): 6.29e-21: 99.7: 14.57
+	At
		186955 BRI1_ARATH (11-320): 3.49e-18: 89.1: 13.03		BAME3_ARATH (332-601): 1.66e-15: 82.3: 17.69
+	Zm
		42762 K7V4X2_MAIZE (12-311): 2.1e-10: 64.9: 16.35		A0A1D6P6J2_MAIZE (275-600): 2.02e-13: 75.1: 24.09