HitPredict

Interactor 1: SOCS2 (O14508)
Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2) (STAT-induced STAT inhibitor 2) (SSI-2)
Gene: SOCS2

Interactor 2: AMRA1 (Q9C0C7)
Activating molecule in BECN1-regulated autophagy protein 1 (DDB1- and CUL4-associated factor 3)
Gene: AMBRA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	28883622, 30166453
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 198 Hs			1 1298
+	Hs
		147446 SOCS3_HUMAN (25-194): 4.14e-48: 158: 29.15		AMRA1_HUMAN (1-1298): 0: 1603: 100.00
+	Hs
		1319011 CISH_HUMAN (3-198): 4.83e-44: 149: 38.29		AMRA1_HUMAN (1-1298): 0: 1603: 100.00
+	Hs
		147558 SOCS6_HUMAN (2-196): 4.82e-41: 147: 31.03		AMRA1_HUMAN (1-1298): 0: 1603: 100.00
+	Hs
		181893 SOCS1_HUMAN (32-198): 8.74e-41: 139: 31.77		AMRA1_HUMAN (1-1298): 0: 1603: 100.00
+	Hs
		412300 FYN_HUMAN (14-172): 9.8e-47: 162: 14.97		SNR40_HUMAN (45-329): 6.16e-55: 197: 11.75
+	Hs
		181906 SOCS1_HUMAN (32-198): 8.74e-41: 139: 31.77		WSB1_HUMAN (57-256): 4.52e-15: 81.3: 13.51