HitPredict

Interactor 1: CDKA1 (O14519)
Cyclin-dependent kinase 2-associated protein 1 (CDK2-associated protein 1) (Deleted in oral cancer 1) (DOC-1) (Putative oral cancer suppressor)
Gene: CDK2AP1

Interactor 2: RBBP4 (Q09028)
Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)
Gene: RBBP4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.732

Property	Details
Experiments	27705803, 33961781, 26496610, 24981860, 20523938, 25123934
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0007049 - cell cycle and 1 others more... GO:0016581 - NuRD complex
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 115 Hs			1 425
+	Hs
		146822 CDKA1_HUMAN (1-115): 1.29e-60: 183: 100.00		RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20
+	Hs
		279796 CDKA2_HUMAN (19-115): 6.1e-40: 131: 66.00		RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00
+	Hs
		279804 CDKA2_HUMAN (19-115): 6.1e-40: 131: 66.00		RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20
+	Hs
		146860 CDKA1_HUMAN (1-115): 1.29e-60: 183: 100.00		TBL1R_HUMAN (109-424): 2.86e-60: 205: 16.52
+	Hs
		146778 CDKA1_HUMAN (1-115): 1.29e-60: 183: 100.00		TBL1X_HUMAN (207-424): 3.72e-35: 138: 17.63
+	Dm
		115156 M9PEA2_DROME (37-114): 1.29e-26: 101: 58.97		CAF1_DROME (226-419): 3.68e-29: 119: 18.36