HitPredict

Interactor 1: PFD5 (Q9VCZ8)
Probable prefoldin subunit 5
Gene: Pfdn5

Interactor 2: PFD2 (Q9VTE5)
Probable prefoldin subunit 2
Gene: Pfdn2

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	1.00	0.901

Property	Details
Experiments	27025979, 37061542, 22036573, 19079254, 38944040
Identification Methods	affinity chromatography technology, two hybrid, two hybrid array, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Prefoldin~Prefoldin_2
Common GO terms	GO:0005737 - cytoplasm GO:0006457 - protein folding GO:0016272 - prefoldin complex GO:0051082 - unfolded protein binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 168 Dm			1 143
+	Hs
		1404691 PFD5_HUMAN (10-163): 5.36e-56: 174: 35.71		PFD2_HUMAN (5-141): 5.36e-43: 140: 48.55
+	Ce
		1170558 PFD5_CAEEL (12-157): 4.15e-51: 162: 29.25		PFD2_CAEEL (12-131): 2.44e-30: 108: 33.33
+	Sc
		816746 PFD5_YEAST (11-168): 1.42e-44: 146: 33.13		PFD2_YEAST (14-117): 1.03e-25: 95.5: 32.69