Protein: PFD5
Prefoldin subunit 5 (Genes involved in microtubule biogenesis protein 5) (Gim complex subunit 5) (GimC subunit 5)

Gene: PFD5, GIM5
Organism: Saccharomyces cerevisiae S288C
Interactions: 92
UniProt ID: Q04493

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0006457 - protein folding
GO:0007021 - tubulin complex assembly
GO:0015631 - tubulin binding
GO:0016272 - prefoldin complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

871561

PFD3
Prefoldin subunit 3

9

4

Small-scale

0.971

High

912443

PFD6
Prefoldin subunit 6

7

4

Small-scale

0.962

High

924489

PFD4
Prefoldin subunit 4

5

2

Small-scale

0.903

High

816746

PFD2
Prefoldin subunit 2

4

3

Small-scale

0.881

High

863727

PFD1
Prefoldin subunit 1

3

0

High-throughput

0.811

High

554048

TCPA
T-complex protein 1 subunit alpha

1

2

Small-scale

0.575

High

819749

SSB2
Ribosome-associated molecular chaperone SSB2

2

3

High-throughput

0.552

High

920686

TBG
Tubulin gamma chain

1

8

Small-scale

0.515

High

1046761

NAA25
N-terminal acetyltransferase B complex subunit MDM20

1

0

High-throughput

0.513

High

793993

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

6

High-throughput

0.489

High

1046764

CMR1
DNA damage-binding protein CMR1

1

6

High-throughput

0.481

High

796367

FL2D
Protein MUM2

1

0

High-throughput

0.460

High

1046752

ARR1
Arsenical-resistance protein ARR1

1

0

High-throughput

0.460

High

735155

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

453786

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.445

High

486306

TBA1
Tubulin alpha-1 chain

1

6

Small-scale

0.445

High

525094

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

546211

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.445

High

753139

NIP80
Protein NIP100

1

2

High-throughput

0.445

High

789792

ADCS
Aminodeoxychorismate synthase

1

1

High-throughput

0.445

High

487966

TRNL
tRNA ligase

1

0

High-throughput

0.426

High

560761

KIN2
Serine/threonine-protein kinase KIN2

1

0

High-throughput

0.426

High

569548

GCY1
Glycerol 2-dehydrogenase

1

0

High-throughput

0.426

High

575611

PP2B2
Serine/threonine-protein phosphatase 2B catalytic subunit A2

1

0

High-throughput

0.426

High

671103

SIS1
Protein SIS1

1

0

High-throughput

0.426

High

735557

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

0

High-throughput

0.426

High

740692

CBS
Cystathionine beta-synthase

1

0

High-throughput

0.426

High

748149

RPC6
DNA-directed RNA polymerase III subunit RPC6

1

0

High-throughput

0.426

High

751787

PRP8
Pre-mRNA-splicing factor 8

1

0

High-throughput

0.426

High

757906

UBX1
UBX domain-containing protein 1

1

0

High-throughput

0.426

High

763292

SGS1
ATP-dependent helicase SGS1

1

0

High-throughput

0.426

High

791922

AAP1
Alanine/arginine aminopeptidase

1

0

High-throughput

0.426

High

793659

ARL1
ADP-ribosylation factor-like protein 1

1

0

High-throughput

0.426

High

809062

POP2
Poly(A) ribonuclease POP2

1

0

High-throughput

0.426

High

816579

YEC5
Uncharacterized protein YEL025C

1

0

High-throughput

0.426

High

820280

WRIP1
DNA-dependent ATPase MGS1

1

0

High-throughput

0.426

High

824546

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.426

High

825724

CSN11
Cop9 signalosome complex subunit 11

1

0

High-throughput

0.426

High

849776

RIM15
Serine/threonine-protein kinase RIM15

1

0

High-throughput

0.426

High

918004

PALF
pH-response regulator protein palF/RIM8

1

0

High-throughput

0.426

High

919342

RTS3
Protein phosphatase type 2A regulatory subunit RTS3

1

0

High-throughput

0.426

High

923949

ATG2
Autophagy-related protein 2

1

0

High-throughput

0.426

High

923960

YNX4
Uncharacterized globin-like protein YNL234W

1

0

High-throughput

0.426

High

1042985

THADA
tRNA

1

0

High-throughput

0.426

High

1046749

KYNU
Kynureninase

1

0

High-throughput

0.426

High

1046756

NOB1
20S-pre-rRNA D-site endonuclease NOB1

1

0

High-throughput

0.426

High

1046760

SFI1
Protein SFI1

1

0

High-throughput

0.426

High

1046762

RTN2
Reticulon-like protein 2

1

0

High-throughput

0.426

High

743134

STH1
Nuclear protein STH1/NPS1

1

1

High-throughput

0.407

High

744163

BRR2
Pre-mRNA-splicing helicase BRR2

1

2

High-throughput

0.407

High

823033

ATAD2
ATPase histone chaperone YTA7

1

2

High-throughput

0.407

High

864513

MTR4
ATP-dependent RNA helicase DOB1

1

2

High-throughput

0.407

High

948650

ACT
Actin

1

1

Small-scale

0.407

High

1030398

CTF4
DNA polymerase alpha-binding protein

1

5

High-throughput

0.407

High

1042315

PKH3
Serine/threonine-protein kinase PKH3

1

1

High-throughput

0.407

High

1046748

ENT2
Epsin-2

1

2

High-throughput

0.407

High

1046751

RSC2
Chromatin structure-remodeling complex subunit RSC2

1

1

High-throughput

0.407

High

1046755

RIX7
Ribosome biogenesis ATPase RIX7

1

1

High-throughput

0.407

High

737042

CDC3
Cell division control protein 3

1

0

High-throughput

0.251

Low

749723

TYE7
Transcription factor TYE7

1

0

High-throughput

0.251

Low

708128

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

877902

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

368052

ENO2
Enolase 2

1

0

High-throughput

0.232

Low

399316

PYRF
Orotidine 5'-phosphate decarboxylase

1

0

High-throughput

0.232

Low

484794

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.232

Low

503955

RL27B
Large ribosomal subunit protein eL27B

1

0

High-throughput

0.232

Low

575368

EI2BA
Translation initiation factor eIF2B subunit alpha

1

0

High-throughput

0.232

Low

635989

ODO1
2-oxoglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.232

Low

672782

SNT1
Probable DNA-binding protein SNT1

1

0

High-throughput

0.232

Low

713591

RIF1
Telomere length regulator protein RIF1

1

0

High-throughput

0.232

Low

757534

NCBP1
Nuclear cap-binding protein complex subunit 1

1

0

High-throughput

0.232

Low

779836

SIS2
Phosphopantothenoylcysteine decarboxylase subunit SIS2

1

0

High-throughput

0.232

Low

794219

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

0

High-throughput

0.232

Low

797052

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.232

Low

803480

TCD1
tRNA threonylcarbamoyladenosine dehydratase 1

1

0

High-throughput

0.232

Low

817711

IES5
Ino eighty subunit 5

1

0

High-throughput

0.232

Low

824669

BNR1
BNI1-related protein 1

1

0

High-throughput

0.232

Low

865370

YJ00
UPF0508 protein YJR030C

1

0

High-throughput

0.232

Low

866030

LIH1
Putative lipase LIH1

1

0

High-throughput

0.232

Low

916386

CWH41
Mannosyl-oligosaccharide glucosidase

1

0

High-throughput

0.232

Low

918173

SWC4
SWR1-complex protein 4

1

0

High-throughput

0.232

Low

1033861

KIN4
Serine/threonine-protein kinase KIN4

1

0

High-throughput

0.232

Low

1036404

UTP6
U3 small nucleolar RNA-associated protein 6

1

0

High-throughput

0.232

Low

1038749

XRN2
5'-3' exoribonuclease 2

1

0

High-throughput

0.232

Low

1046750

EAF1
Chromatin modification-related protein EAF1

1

0

High-throughput

0.232

Low

1046753

YD306
F-box protein YDR306C

1

0

High-throughput

0.232

Low

1046754

YD062
Putative uncharacterized protein YDL062W

1

0

High-throughput

0.232

Low

1046757

DIA2
Protein DIA2

1

0

High-throughput

0.232

Low

1046758

NSL1
Kinetochore-associated protein NSL1

1

0

High-throughput

0.232

Low

1046759

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.232

Low

1046763

OSH2
Oxysterol-binding protein homolog 2

1

0

High-throughput

0.232

Low

1046765

ATC8
Probable phospholipid-transporting ATPase DNF3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025