Protein: PFD2
Prefoldin subunit 2 (Genes involved in microtubule biogenesis protein 4) (Gim complex subunit 4) (GimC subunit 4)

Gene: PFD2, GIM4
Organism: Saccharomyces cerevisiae S288C
Interactions: 125
UniProt ID: P40005

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0006457 - protein folding
GO:0007021 - tubulin complex assembly
GO:0015631 - tubulin binding
GO:0016272 - prefoldin complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

816722

PFD3
Prefoldin subunit 3

5

4

Small-scale

0.916

High

816726

PFD6
Prefoldin subunit 6

4

2

Small-scale

0.896

High

816746

PFD5
Prefoldin subunit 5

4

3

Small-scale

0.881

High

816729

PFD4
Prefoldin subunit 4

3

2

High-throughput

0.855

High

816717

PFD1
Prefoldin subunit 1

3

0

High-throughput

0.787

High

816714

BUD27
Bud site selection protein 27

1

0

High-throughput

0.589

High

646043

KIN3
Serine/threonine-protein kinase KIN3

1

1

High-throughput

0.481

High

815644

LIS1
Nuclear distribution protein PAC1

1

7

High-throughput

0.481

High

438303

NOT3
General negative regulator of transcription subunit 3

1

0

High-throughput

0.460

High

735627

SMY1
Kinesin-related protein SMY1

1

0

High-throughput

0.460

High

782574

DAD2
DASH complex subunit DAD2

1

0

High-throughput

0.460

High

816730

NST1
Stress response protein NST1

1

0

High-throughput

0.460

High

816736

MDM1
Structural protein MDM1

1

0

High-throughput

0.460

High

816744

VPS20
Vacuolar protein sorting-associated protein 20

1

0

High-throughput

0.460

High

816750

NDE1
Nuclear distribution protein nudE homolog 1

1

0

High-throughput

0.460

High

816755

SRL2
Protein SRL2

1

0

High-throughput

0.460

High

504576

YD15B
Transposon Ty1-DR6 Gag-Pol polyprotein

1

1

High-throughput

0.445

High

704872

KIP1
Kinesin-like protein KIP1

1

2

High-throughput

0.445

High

739875

RPD3
Histone deacetylase RPD3

1

2

High-throughput

0.445

High

763832

SKI2
Antiviral helicase SKI2

1

2

High-throughput

0.445

High

781541

ALY1
Arrestin-related trafficking adapter 6

1

1

High-throughput

0.445

High

793649

ARL1
ADP-ribosylation factor-like protein 1

1

1

High-throughput

0.445

High

806921

YH19
Putative uncharacterized protein YHR219W

1

2

High-throughput

0.445

High

816709

YRF12
Y' element ATP-dependent helicase protein 1 copy 2

1

2

High-throughput

0.445

High

816710

6P21
6-phosphofructo-2-kinase 1

1

1

High-throughput

0.445

High

816719

ALY2
Arrestin-related trafficking adapter 3

1

1

High-throughput

0.445

High

816727

ASCC3
RQC trigger complex helicase SLH1

1

2

High-throughput

0.445

High

816743

YM13B
Transposon Ty1-MR1 Gag-Pol polyprotein

1

1

High-throughput

0.445

High

816762

YL066
Y' element ATP-dependent helicase YLL066C

1

2

High-throughput

0.445

High

700007

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

1

High-throughput

0.439

High

359238

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

High-throughput

0.426

High

394594

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

460978

LTE1
Guanine nucleotide exchange factor LTE1

1

0

High-throughput

0.426

High

464328

OAT
Ornithine aminotransferase

1

0

High-throughput

0.426

High

524057

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.426

High

572593

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.426

High

656479

KC11
Casein kinase I homolog 1

1

0

High-throughput

0.426

High

670751

SIS1
Protein SIS1

1

0

High-throughput

0.426

High

673703

KCC4
Probable serine/threonine-protein kinase KCC4

1

0

High-throughput

0.426

High

724293

ZIP1
Synaptonemal complex protein ZIP1

1

0

High-throughput

0.426

High

746734

KPR1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.426

High

750046

PDR3
Transcription factor PDR3

1

0

High-throughput

0.426

High

751406

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.426

High

753088

NIP80
Protein NIP100

1

0

High-throughput

0.426

High

757814

YBF5
Deoxyribonuclease Tat-D

1

0

High-throughput

0.426

High

757881

UBX1
UBX domain-containing protein 1

1

0

High-throughput

0.426

High

791905

AAP1
Alanine/arginine aminopeptidase

1

0

High-throughput

0.426

High

803125

ECM29
Proteasome component ECM29

1

0

High-throughput

0.426

High

806460

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.426

High

816712

PRK1
Actin-regulating kinase PRK1

1

0

High-throughput

0.426

High

816715

DUG1
Cys-Gly metallodipeptidase DUG1

1

0

High-throughput

0.426

High

816724

BRO1
Vacuolar-sorting protein BRO1

1

0

High-throughput

0.426

High

816725

INP52
Polyphosphatidylinositol phosphatase INP52

1

0

High-throughput

0.426

High

816731

IDHH
Isocitrate dehydrogenase [NADP]

1

0

High-throughput

0.426

High

816749

ARO10
Transaminated amino acid decarboxylase

1

0

High-throughput

0.426

High

816752

YL419
Putative ATP-dependent RNA helicase YLR419W

1

0

High-throughput

0.426

High

816754

AVO1
Target of rapamycin complex 2 subunit AVO1

1

0

High-throughput

0.426

High

816758

RTN2
Reticulon-like protein 2

1

0

High-throughput

0.426

High

816761

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.426

High

534267

RPA1
DNA-directed RNA polymerase I subunit RPA190

1

3

High-throughput

0.407

High

633552

SAR1
Small COPII coat GTPase SAR1

1

1

High-throughput

0.407

High

699405

CIN8
Kinesin-like protein CIN8

1

2

High-throughput

0.407

High

699953

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

3

High-throughput

0.407

High

735337

ERG3
Delta(7)-sterol 5(6)-desaturase ERG3

1

1

High-throughput

0.407

High

778846

AP1B1
AP-1 complex subunit beta-1

1

1

High-throughput

0.407

High

808679

SUR2
Sphingolipid C4-hydroxylase SUR2

1

1

High-throughput

0.407

High

816734

CTR9
RNA polymerase-associated protein CTR9

1

1

High-throughput

0.407

High

816735

CTF4
DNA polymerase alpha-binding protein

1

3

High-throughput

0.407

High

577305

NSP1
Nucleoporin NSP1

2

0

High-throughput

0.307

High

639497

RE107
Recombination protein 107

1

0

High-throughput

0.251

Low

736982

CDC3
Cell division control protein 3

1

0

High-throughput

0.251

Low

816716

GON7
EKC/KEOPS complex subunit GON7

1

0

High-throughput

0.251

Low

816745

SPC24
Kinetochore protein SPC24

1

0

High-throughput

0.251

Low

816757

ERP3
Protein ERP3

1

0

High-throughput

0.251

Low

452026

TOM70
Mitochondrial import receptor subunit TOM70

1

0

Small-scale

0.249

Low

707190

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

150171

THP2
THO complex subunit THP2

1

0

High-throughput

0.232

Low

368676

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.232

Low

399312

PYRF
Orotidine 5'-phosphate decarboxylase

1

0

High-throughput

0.232

Low

503922

RL27B
Large ribosomal subunit protein eL27B

1

0

High-throughput

0.232

Low

597467

EF3A
Elongation factor 3A

1

0

High-throughput

0.232

Low

618590

FAS2
Fatty acid synthase subunit alpha

1

0

High-throughput

0.232

Low

636584

PSA7
Probable proteasome subunit alpha type-7

1

0

High-throughput

0.232

Low

640713

RT28
Small ribosomal subunit protein uS15m

1

0

High-throughput

0.232

Low

682879

MSH1
DNA mismatch repair protein MSH1, mitochondrial

1

0

High-throughput

0.232

Low

700065

FUN19
SWIRM domain-containing protein FUN19

1

0

High-throughput

0.232

Low

704126

TRK2
Low-affinity potassium transport protein

1

0

High-throughput

0.232

Low

713580

RIF1
Telomere length regulator protein RIF1

1

0

High-throughput

0.232

Low

724878

RAD16
DNA repair protein RAD16

1

0

High-throughput

0.232

Low

740337

SNQ2
Protein SNQ2

1

0

High-throughput

0.232

Low

744974

YHH7
UPF0744 protein YSC83

1

0

High-throughput

0.232

Low

746067

SEC6
Exocyst complex component SEC6

1

0

High-throughput

0.232

Low

747727

SMC1
Structural maintenance of chromosomes protein 1

1

0

High-throughput

0.232

Low

751046

XRS2
DNA repair protein XRS2

1

0

High-throughput

0.232

Low

758449

YKK0
Probable intramembrane protease YKL100C

1

0

High-throughput

0.232

Low

793481

MAK5
ATP-dependent RNA helicase MAK5

1

0

High-throughput

0.232

Low

797178

ATG14
Autophagy-related protein 14

1

0

High-throughput

0.232

Low

798034

YB75
Uncharacterized protein YBR225W

1

0

High-throughput

0.232

Low

811537

MNN1
Alpha-1,3-mannosyltransferase MNN1

1

0

High-throughput

0.232

Low

812970

YAO0
Putative uncharacterized protein YAR070C

1

0

High-throughput

0.232

Low

813383

NPT1
Nicotinate phosphoribosyltransferase

1

0

High-throughput

0.232

Low

815299

IF4F2
Eukaryotic initiation factor 4F subunit p130

1

0

High-throughput

0.232

Low

816711

BNR1
BNI1-related protein 1

1

0

High-throughput

0.232

Low

816713

SPG5
Stationary phase protein 5

1

0

High-throughput

0.232

Low

816718

MRX5
MIOREX complex component 5

1

0

High-throughput

0.232

Low

816720

LIH1
Putative lipase LIH1

1

0

High-throughput

0.232

Low

816721

IML1
Vacuolar membrane-associated protein IML1

1

0

High-throughput

0.232

Low

816723

HOSC
Homocitrate synthase, cytosolic isozyme

1

0

High-throughput

0.232

Low

816728

SUCA
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial

1

0

High-throughput

0.232

Low

816732

ORN
Oligoribonuclease, mitochondrial

1

0

High-throughput

0.232

Low

816733

ATPJ
ATP synthase subunit e, mitochondrial

1

0

High-throughput

0.232

Low

816737

UTP6
U3 small nucleolar RNA-associated protein 6

1

0

High-throughput

0.232

Low

816738

VTC3
Vacuolar transporter chaperone 3 complex subunit 3

1

0

High-throughput

0.232

Low

816739

YD541
Putative uncharacterized oxidoreductase YDR541C

1

0

High-throughput

0.232

Low

816740

ATP25
ATPase synthesis protein 25, mitochondrial

1

0

High-throughput

0.232

Low

816741

CG121
EKC/KEOPS complex subunit CGI121

1

0

High-throughput

0.232

Low

816742

POLH
DNA polymerase eta

1

0

High-throughput

0.232

Low

816747

YMI9
Putative uncharacterized protein YML089C

1

0

High-throughput

0.232

Low

816748

EAF1
Chromatin modification-related protein EAF1

1

0

High-throughput

0.232

Low

816751

CDC73
Cell division control protein 73

1

0

High-throughput

0.232

Low

816753

YD073
UPF0592 protein YDL073W

1

0

High-throughput

0.232

Low

816756

MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1

1

0

High-throughput

0.232

Low

816759

NOP56
Nucleolar protein 56

1

0

High-throughput

0.232

Low

816760

SET6
Potential protein lysine methyltransferase SET6

1

0

High-throughput

0.232

Low

816763

PET20
Protein PET20, mitochondrial

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025