Interactor 1: LEG9 (O08573)
Galectin-9 (Gal-9)
Gene: Lgals9

Interactor 2: HAVR2 (Q8VIM0)
Hepatitis A virus cellular receptor 2 homolog (HAVcr-2) (T-cell immunoglobulin and mucin domain-containing protein 3) (TIMD-3) (T-cell immunoglobulin mucin receptor 3) (TIM-3) (T-cell membrane protein 3) (CD antigen CD366)
Gene: Havcr2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 16286920
Identification Methods anti tag coimmunoprecipitation, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Gal-bind_lectin~V-set
Common GO terms GO:0001819 - positive regulation of cytokine production
GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0032689 - negative regulation of type II interferon production
GO:0032722 - positive regulation of chemokine production
and 6 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 353
Mm

1 281
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025