HitPredict

Interactor 1: DC1I1 (O14576)
Cytoplasmic dynein 1 intermediate chain 1 (Cytoplasmic dynein intermediate chain 1) (Dynein intermediate chain 1, cytosolic) (DH IC-1)
Gene: DYNC1I1

Interactor 2: NDEL1 (Q9GZM8)
Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin-associated protein 1)
Gene: NDEL1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	22159412, 14970193, 31815665, 19927128
Identification Methods	pull down, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0005829 - cytosol GO:0005874 - microtubule GO:0008017 - microtubule binding GO:0047496 - vesicle transport along microtubule
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 645 Hs			1 345
+	Mm
		291687 DC1I1_MOUSE (1-645): 1.63e-144: 435: 95.35		NDEL1_MOUSE (1-345): 7.05e-67: 215: 95.94
+	Mm
		291686 DC1I1_MOUSE (1-645): 1.63e-144: 435: 95.35		NDE1_MOUSE (3-345): 7.34e-47: 164: 54.31
+	Dm
		1096840 DYIN_DROME (6-635): 2.04e-103: 330: 46.46		NDE1_DROME (4-236): 3e-29: 116: 37.77
+	Hs
		148929 DNAI4_HUMAN (25-612): 2.85e-84: 284: 18.03		CTRO_HUMAN (12-211): 2.55e-24: 106: 19.32
+	Hs
		724952 FBXW7_HUMAN (4-601): 3.88e-73: 251: 12.71		MYH9_HUMAN (2-223): 7.48e-24: 105: 17.57
+	Hs
		1148943 FBXW7_HUMAN (4-601): 3.88e-73: 251: 12.71		CYTSA_HUMAN (2-331): 7.36e-23: 102: 16.06
+	Hs
		725215 FBXW7_HUMAN (4-601): 3.88e-73: 251: 12.71		MYH10_HUMAN (2-228): 6.16e-23: 102: 18.06
+	Dm
		1181501 LIS1_DROME (325-635): 4.98e-66: 224: 14.20		NDE1_DROME (4-236): 3e-29: 116: 37.77
+	Dm
		116378 CAF1_DROME (208-609): 1.82e-62: 215: 15.20		M9PI41_DROME (3-205): 2.04e-30: 124: 18.57
+	Hs
		1189782 FBXW7_HUMAN (4-601): 3.88e-73: 251: 12.71		MYH14_HUMAN (2-216): 1.78e-13: 73.5: 19.54
+	Hs
		793028 LIS1_HUMAN (11-371): 4.83e-19: 91.8: 9.46		NDEL1_HUMAN (1-345): 1.8e-67: 217: 100.00
+	Rn
		925835 LIS1_RAT (11-371): 4.17e-19: 92.2: 9.46		NDEL1_RAT (1-345): 7.05e-67: 215: 95.94
+	Mm
		925843 LIS1_MOUSE (11-371): 4.17e-19: 92.2: 9.46		NDEL1_MOUSE (1-345): 7.05e-67: 215: 95.94
+	Ce
		220392 LIS1_CAEEL (199-563): 1.55e-60: 209: 10.82		NUD2_CAEEL (24-211): 2.06e-19: 89: 24.08
+	Hs
		148610 WDR5_HUMAN (135-467): 5.01e-40: 151: 11.18		CTRO_HUMAN (12-211): 2.55e-24: 106: 19.32
+	Mm
		925842 LIS1_MOUSE (11-371): 4.17e-19: 92.2: 9.46		NDE1_MOUSE (3-345): 7.34e-47: 164: 54.31
+	Hs
		728492 POC1A_HUMAN (115-418): 4.88e-32: 130: 7.37		MYH11_HUMAN (2-223): 2.17e-26: 112: 18.92
+	Hs
		793036 LIS1_HUMAN (11-371): 4.83e-19: 91.8: 9.46		NDE1_HUMAN (3-321): 2.95e-41: 149: 55.25
+	Hs
		903334 WDR5_HUMAN (135-467): 5.01e-40: 151: 11.18		MYH14_HUMAN (2-216): 1.78e-13: 73.5: 19.54
+	Hs
		1022845 STRN3_HUMAN (364-625): 1.19e-14: 79.6: 13.60		CTTB2_HUMAN (1-342): 7.57e-11: 65.4: 13.50