HitPredict

Interactor 1: CTRO (O14578)
Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)
Gene: CIT

Interactor 2: ML12B (O14950)
Myosin regulatory light chain 12B (MLC-2A) (MLC-2) (Myosin regulatory light chain 2-B, smooth muscle isoform) (Myosin regulatory light chain 20 kDa) (MLC20) (Myosin regulatory light chain MRLC2) (SHUJUN-1)
Gene: MYL12B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EF-hand_7~Pkinase
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2027 Hs			1 172
+	Hs
		148410 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MYL9_HUMAN (1-172): 2.61e-66: 201: 93.02
+	Hs
		148383 CTRO_HUMAN (1-2027): 0: 1212: 100.00		ML12A_HUMAN (15-172): 2.3e-65: 199: 99.37
+	Hs
		624380 AKT3_HUMAN (44-417): 2.46e-124: 403: 30.31		MYL9_HUMAN (1-172): 2.61e-66: 201: 93.02
+	Dm
		116375 M9PI41_DROME (554-1859): 9.84e-96: 347: 15.45		SQH_DROME (1-172): 2.29e-61: 189: 81.03
+	At
		1104924 CDPK4_ARATH (73-547): 7.34e-127: 410: 20.63		CDPK4_ARATH (37-172): 5.35e-13: 67.6: 19.15
+	At
		1105900 CDPKB_ARATH (75-547): 1.64e-126: 409: 20.71		CDPKB_ARATH (103-172): 1.13e-12: 66.8: 27.14
+	Gm
		1196117 Q84P28_SOYBN (80-547): 1.63e-126: 409: 20.93		Q84P28_SOYBN (25-112): 1.15e-10: 61: 18.28
+	At
		989461 KIN10_ARATH (96-367): 2.92e-120: 392: 27.84		CDPK1_ARATH (62-172): 3.22e-14: 71: 20.18
+	At
		483143 CIPKO_ARATH (87-529): 6.92e-118: 383: 20.89		CALM4_ARATH (98-171): 7.33e-17: 74.9: 24.32
+	At
		187626 CIPKD_ARATH (74-544): 3.7e-117: 383: 22.43		CDPKF_ARATH (96-172): 1.59e-14: 72.2: 28.21
+	At
		188340 CIPKO_ARATH (87-529): 6.92e-118: 383: 20.89		CML8_ARATH (90-171): 3.04e-12: 62.8: 20.73
+	At
		976670 CIPKO_ARATH (87-529): 6.92e-118: 383: 20.89		CALM6_ARATH (32-93): 7.82e-12: 61.7: 31.82
+	At
		886601 CIPKO_ARATH (87-529): 6.92e-118: 383: 20.89		CALM7_ARATH (20-93): 8.05e-09: 53.3: 24.36
+	Hs
		580656 MRCKA_HUMAN (536-1061): 4.38e-32: 139: 11.82		ML12A_HUMAN (15-172): 2.3e-65: 199: 99.37
+	Hs
		254439 ROCK2_HUMAN (864-1552): 1.55e-37: 157: 12.16		MLRV_HUMAN (9-166): 1.98e-54: 171: 57.23
+	At
		483153 Q9LW66_ARATH (88-455): 9.25e-65: 233: 35.18		CALM4_ARATH (98-171): 7.33e-17: 74.9: 24.32
+	At
		188349 Q9LW66_ARATH (88-455): 9.25e-65: 233: 35.18		CML8_ARATH (90-171): 3.04e-12: 62.8: 20.73
+	At
		976679 Q9LW66_ARATH (88-455): 9.25e-65: 233: 35.18		CALM6_ARATH (32-93): 7.82e-12: 61.7: 31.82
+	At
		886616 Q9LW66_ARATH (88-455): 9.25e-65: 233: 35.18		CALM7_ARATH (20-93): 8.05e-09: 53.3: 24.36
+	Dm
		576952 Q961D4_DROME (682-1366): 1.1e-37: 158: 11.24		MLR_DROME (13-163): 1.86e-29: 109: 42.21