Interactor 1: GSH0 (O09172)
Glutamate--cysteine ligase regulatory subunit (GCS light chain) (Gamma-ECS regulatory subunit) (Gamma-glutamylcysteine synthetase regulatory subunit) (Glutamate--cysteine ligase modifier subunit)
Gene: Gclm
Interactor 2: GSH1 (P97494)
Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase)
Gene: Gclc
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 0.60 | 0.501 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16081425 |
| Identification Methods | pull down |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0004357 - glutamate-cysteine ligase activity GO:0006534 - cysteine metabolic process GO:0006536 - glutamate metabolic process GO:0006749 - glutathione metabolic process GO:0006750 - glutathione biosynthetic process and 17 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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| + | Dm | |
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
