HitPredict

Interactor 1: CTRO (O14578)
Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)
Gene: CIT

Interactor 2: PLSI (Q14651)
Plastin-1 (Intestine-specific plastin) (I-plastin)
Gene: PLS1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EF-hand_7~Pkinase
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 2027 Hs			1 629
+	Hs
		148345 CTRO_HUMAN (1-2027): 0: 1212: 100.00		PLST_HUMAN (2-628): 0: 641: 75.32
+	Hs
		149277 CTRO_HUMAN (1-2027): 0: 1212: 100.00		SPTN4_HUMAN (390-629): 3.04e-71: 253: 20.16
+	Hs
		148722 CTRO_HUMAN (1-2027): 0: 1212: 100.00		ACTN3_HUMAN (391-626): 2.82e-50: 189: 20.66
+	Hs
		148142 CTRO_HUMAN (1-2027): 0: 1212: 100.00		SPTN2_HUMAN (382-629): 3.19e-49: 187: 21.09
+	Hs
		148330 CTRO_HUMAN (1-2027): 0: 1212: 100.00		SPTB1_HUMAN (382-629): 3.26e-49: 187: 19.14
+	Hs
		149428 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MACF1_HUMAN (381-620): 5.1e-49: 187: 21.05
+	Hs
		148171 CTRO_HUMAN (1-2027): 0: 1212: 100.00		ACTN4_HUMAN (379-626): 3.78e-49: 186: 19.69
+	Hs
		148841 CTRO_HUMAN (1-2027): 0: 1212: 100.00		PLEC_HUMAN (374-628): 1.14e-48: 186: 20.91
+	Hs
		148339 CTRO_HUMAN (1-2027): 0: 1212: 100.00		ACTN1_HUMAN (378-626): 7.32e-49: 185: 19.61
+	Hs
		148690 CTRO_HUMAN (1-2027): 0: 1212: 100.00		SPTB2_HUMAN (382-629): 8.7e-48: 183: 19.53
+	Hs
		148463 CTRO_HUMAN (1-2027): 0: 1212: 100.00		ACTN2_HUMAN (391-626): 2.79e-47: 180: 19.84
+	Rn
		1144340 AKT3_RAT (44-404): 7.24e-122: 395: 31.37		SPTN2_RAT (382-629): 8.48e-49: 186: 21.09
+	Hs
		623875 KPCL_HUMAN (1355-1514): 4.34e-12: 73.3: 16.36		PLEC_HUMAN (374-628): 1.14e-48: 186: 20.91