Interactor 1: HCN4 (Q9Y3Q4)
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Gene: HCN4
Interactor 2: KCNE2 (Q9Y6J6)
Potassium voltage-gated channel subfamily E member 2 (MinK-related peptide 1) (MiRP1) (Minimum potassium ion channel-related peptide 1) (Potassium channel subunit beta MiRP1)
Gene: KCNE2
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.621 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12856183 |
| Identification Methods | two hybrid |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ISK_Channel~Ion_trans |
| Common GO terms | GO:0005886 - plasma membrane GO:0071805 - potassium ion transmembrane transport GO:0086091 - regulation of heart rate by cardiac conduction GO:1990573 - potassium ion import across plasma membrane |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
