HitPredict

Interactor 1: CTRO (O14578)
Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)
Gene: CIT

Interactor 2: SRSF8 (Q9BRL6)
Serine/arginine-rich splicing factor 8 (Pre-mRNA-splicing factor SRP46) (Splicing factor SRp46) (Splicing factor, arginine/serine-rich 2B)
Gene: SRSF8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 2027 Hs			1 282
+	Hs
		148692 CTRO_HUMAN (1-2027): 0: 1212: 100.00		SRSF2_HUMAN (1-100): 1.3e-41: 144: 80.00
+	Hs
		148763 CTRO_HUMAN (1-2027): 0: 1212: 100.00		PABP4_HUMAN (2-103): 9.14e-22: 96.7: 19.61
+	Hs
		148334 CTRO_HUMAN (1-2027): 0: 1212: 100.00		PABP1_HUMAN (2-103): 1.99e-20: 92.9: 18.63
+	Hs
		148894 CTRO_HUMAN (1-2027): 0: 1212: 100.00		PAP1L_HUMAN (2-103): 2.9e-20: 92.1: 22.55
+	Hs
		149282 CTRO_HUMAN (1-2027): 0: 1212: 100.00		PABP3_HUMAN (2-103): 2.88e-19: 89.4: 19.61
+	Hs
		148691 CTRO_HUMAN (1-2027): 0: 1212: 100.00		TIAR_HUMAN (8-102): 5.22e-19: 87.5: 26.32
+	Hs
		964075 KS6B2_HUMAN (57-412): 7.82e-122: 395: 30.44		SRSF2_HUMAN (1-100): 1.3e-41: 144: 80.00
+	Rn
		1144336 AKT3_RAT (44-404): 7.24e-122: 395: 31.37		PABP1_RAT (2-103): 1.85e-20: 92.9: 18.63
+	Hs
		516724 KS6B2_HUMAN (57-412): 7.82e-122: 395: 30.44		PABP1_HUMAN (2-103): 1.99e-20: 92.9: 18.63
+	Sc
		376578 KAPB_YEAST (77-406): 2.85e-122: 393: 29.59		PABP_YEAST (2-103): 2.06e-20: 92.5: 19.61
+	Hs
		116962 SGK1_HUMAN (59-407): 8.42e-121: 390: 31.37		PABP1_HUMAN (2-103): 1.99e-20: 92.9: 18.63