Protein: FOB1
DNA replication fork-blocking protein FOB1

Gene: FOB1
Organism: Saccharomyces cerevisiae S288C
Interactions: 64
UniProt ID: O13329

Gene Ontology (top 5):
GO:0000183 - rDNA heterochromatin formation
GO:0005730 - nucleolus
GO:0006310 - DNA recombination
GO:0006325 - chromatin organization
GO:0007059 - chromosome segregation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

149217

NET1
Nucleolar protein NET1

5

1

Small-scale

0.715

High

149183

SIR2
NAD-dependent histone deacetylase SIR2

7

0

Small-scale

0.706

High

149235

NSI1
RNA polymerase I termination factor

4

1

Small-scale

0.694

High

149226

TOF2
Topoisomerase 1-associated factor 2

3

1

Small-scale

0.660

High

149224

CDC14
Tyrosine-protein phosphatase CDC14

3

0

Small-scale

0.616

High

149175

FOB1
DNA replication fork-blocking protein FOB1

3

0

Small-scale

0.612

High

149191

SPO12
Sporulation-specific protein 12

2

0

Small-scale

0.593

High

149176

H2B1
Histone H2B.1

2

1

Small-scale

0.571

High

149213

ATAD2
ATPase histone chaperone YTA7

2

0

High-throughput

0.547

High

149189

SSB1
Ribosome-associated molecular chaperone SSB1

2

1

High-throughput

0.504

High

149180

TOP1
DNA topoisomerase 1

1

0

Small-scale

0.493

High

149228

NOG1
Nucleolar GTP-binding protein 1

1

0

Small-scale

0.493

High

149185

SPT2
Protein SPT2

1

0

High-throughput

0.486

High

149211

LSM5
LSM complex subunit LSM5

1

0

High-throughput

0.486

High

149177

H2B2
Histone H2B.2

1

1

Small-scale

0.479

High

149181

H2A1
Histone H2A.1

1

1

Small-scale

0.479

High

149182

H2A2
Histone H2A.2

1

1

Small-scale

0.479

High

149192

REB1
DNA-binding protein REB1

1

1

Small-scale

0.470

High

149227

SLU7
Pre-mRNA-splicing factor SLU7

1

0

Small-scale

0.460

High

149232

APC5
Anaphase-promoting complex subunit 5

1

0

Small-scale

0.460

High

149178

H4
Histone H4

1

0

Small-scale

0.458

High

149193

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

0

High-throughput

0.458

High

149197

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

149207

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

149220

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

149221

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.458

High

149230

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

149222

ZDS2
Protein ZDS2

1

0

High-throughput

0.438

High

149200

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.426

High

149201

CBF3A
Centromere DNA-binding protein complex CBF3 subunit A

1

0

High-throughput

0.426

High

149209

SET3
SET domain-containing protein 3

1

0

High-throughput

0.426

High

149223

H3
Histone H3

1

0

High-throughput

0.426

High

149236

CAF1A
Chromatin assembly factor 1 subunit A

1

0

High-throughput

0.426

High

149186

SWI6
Regulatory protein SWI6

1

1

High-throughput

0.407

High

149187

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.407

High

149188

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.407

High

149196

SWI4
Regulatory protein SWI4

1

1

High-throughput

0.407

High

149202

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.407

High

149212

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.407

High

149199

XPO1
Exportin-1

1

0

High-throughput

0.279

Low

149203

RU1A
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.265

Low

149210

TEM1
Protein TEM1

1

0

High-throughput

0.265

Low

149225

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

1

0

High-throughput

0.265

Low

149195

GRR1
SCF E3 ubiquitin ligase complex F-box protein GRR1

1

0

Small-scale

0.251

Low

149205

PRP8
Pre-mRNA-splicing factor 8

1

0

Small-scale

0.251

Low

149218

MCM6
DNA replication licensing factor MCM6

1

0

Small-scale

0.251

Low

149198

BMH1
Protein BMH1

1

0

High-throughput

0.249

Low

149204

CACP
Carnitine O-acetyltransferase, mitochondrial

1

0

High-throughput

0.249

Low

149214

BNI1
Protein BNI1

1

0

High-throughput

0.249

Low

149219

H1
Histone H1

1

0

Small-scale

0.249

Low

149234

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.249

Low

149194

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.238

Low

149208

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.238

Low

149216

MRX5
MIOREX complex component 5

1

0

High-throughput

0.238

Low

149229

PRP42
U1 small nuclear ribonucleoprotein component PRP42

1

0

High-throughput

0.238

Low

149233

IOC2
ISWI one complex protein 2

1

0

High-throughput

0.238

Low

149237

VPS5
Vacuolar protein sorting-associated protein 5

1

0

High-throughput

0.238

Low

149179

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low

149184

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.232

Low

149190

MCM1
Pheromone receptor transcription factor

1

0

High-throughput

0.232

Low

149206

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

149215

STU2
Protein STU2

1

0

High-throughput

0.232

Low

149231

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025