Protein: NET1
Nucleolar protein NET1

Gene: NET1
Organism: Saccharomyces cerevisiae S288C
Interactions: 167
UniProt ID: P47035

Gene Ontology (top 5):
GO:0000182 - rDNA binding
GO:0000183 - rDNA heterochromatin formation
GO:0001100 - negative regulation of exit from mitosis
GO:0004864 - protein phosphatase inhibitor activity
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

864309

CDC14
Tyrosine-protein phosphatase CDC14

24

1

Small-scale

0.769

High

444778

SIR2
NAD-dependent histone deacetylase SIR2

20

1

Small-scale

0.766

High

149217

FOB1
DNA replication fork-blocking protein FOB1

5

1

Small-scale

0.715

High

864315

TOF2
Topoisomerase 1-associated factor 2

4

2

Small-scale

0.693

High

534278

RPA1
DNA-directed RNA polymerase I subunit RPA190

4

1

Small-scale

0.691

High

364613

CDK1
Cyclin-dependent kinase 1

4

0

Small-scale

0.666

High

864324

LRS4
Monopolin complex subunit LRS4

3

1

Small-scale

0.640

High

644950

RPA2
DNA-directed RNA polymerase I subunit RPA135

4

2

Small-scale

0.623

High

864349

RIO1
Serine/threonine-protein kinase RIO1

2

1

High-throughput

0.611

High

864308

2ABA
Protein phosphatase PP2A regulatory subunit B

2

0

Small-scale

0.609

High

864311

RPA49
DNA-directed RNA polymerase I subunit RPA49

2

1

High-throughput

0.601

High

739981

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

2

1

Small-scale

0.595

High

858233

RPA43
DNA-directed RNA polymerase I subunit RPA43

3

1

Small-scale

0.593

High

667103

CG22
G2/mitotic-specific cyclin-2

2

2

Small-scale

0.585

High

826621

DSN1
Kinetochore-associated protein DSN1

2

1

High-throughput

0.584

High

524396

HSP71
Heat shock protein SSA1

3

2

High-throughput

0.578

High

763932

SPT10
Protein SPT10

2

1

High-throughput

0.571

High

459122

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

2

1

High-throughput

0.561

High

864297

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.561

High

864300

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

High-throughput

0.549

High

864348

SCC1
Sister chromatid cohesion protein 1

2

0

Small-scale

0.547

High

864350

NSI1
RNA polymerase I termination factor

1

0

Small-scale

0.537

High

585973

CSK21
Casein kinase II subunit alpha

1

3

High-throughput

0.536

High

622977

CSK22
Casein kinase II subunit alpha'

1

3

High-throughput

0.536

High

667141

CG23
G2/mitotic-specific cyclin-3

1

2

High-throughput

0.536

High

646458

RAD53
Serine/threonine-protein kinase RAD53

2

1

Small-scale

0.533

High

382189

H4
Histone H4

2

1

High-throughput

0.521

High

822998

ATAD2
ATPase histone chaperone YTA7

2

2

High-throughput

0.521

High

864316

LGE1
Transcriptional regulatory protein LGE1

2

1

High-throughput

0.521

High

864352

H2AZ
Histone H2A.Z

2

1

High-throughput

0.521

High

599377

FUS3
Mitogen-activated protein kinase FUS3

1

0

High-throughput

0.513

High

780156

SDS22
Protein phosphatase 1 regulatory subunit SDS22

1

0

High-throughput

0.513

High

864323

HMO1
High mobility group protein 1

1

0

High-throughput

0.513

High

392965

HSP82
ATP-dependent molecular chaperone HSP82

1

2

High-throughput

0.494

High

806536

UTP9
U3 small nucleolar RNA-associated protein 9

1

0

High-throughput

0.493

High

817589

UTP7
U3 small nucleolar RNA-associated protein 7

1

0

Small-scale

0.493

High

825281

MOB1
DBF2 kinase activator protein MOB1

1

0

High-throughput

0.493

High

560722

KIN2
Serine/threonine-protein kinase KIN2

1

1

High-throughput

0.489

High

794276

CHK1
Serine/threonine-protein kinase CHK1

1

1

High-throughput

0.489

High

809084

DUN1
DNA damage response protein kinase DUN1

1

2

High-throughput

0.489

High

864301

FMP48
Probable serine/threonine-protein kinase FMP48

1

2

High-throughput

0.489

High

864321

VHS1
Serine/threonine-protein kinase VHS1

1

2

High-throughput

0.489

High

864326

CAF1B
Chromatin assembly factor 1 subunit B

1

1

High-throughput

0.489

High

737896

HOG1
Mitogen-activated protein kinase HOG1

1

0

Small-scale

0.480

High

692581

NSR1
Nuclear localization sequence-binding protein

1

1

High-throughput

0.479

High

740734

SRP40
Suppressor protein SRP40

1

1

High-throughput

0.479

High

864018

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

1

High-throughput

0.479

High

864302

RRN9
RNA polymerase I-specific transcription initiation factor RRN9

1

1

High-throughput

0.479

High

764106

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

795960

RRN10
RNA polymerase I-specific transcription initiation factor RRN10

1

0

High-throughput

0.458

High

823716

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.458

High

844516

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

864317

UTP17
NET1-associated nuclear protein 1

1

0

Small-scale

0.458

High

864331

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

864340

SGO1
Shugoshin

1

0

High-throughput

0.458

High

864295

NET1
Nucleolar protein NET1

1

2

High-throughput

0.457

High

670875

SIS1
Protein SIS1

1

1

High-throughput

0.445

High

807102

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

1

High-throughput

0.445

High

864332

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.438

High

864347

SAS10
Something about silencing protein 10

1

0

High-throughput

0.438

High

579652

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.437

High

647153

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

2

High-throughput

0.437

High

700019

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

1

High-throughput

0.437

High

707499

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

708758

TF3B
Transcription factor IIIB 70 kDa subunit

1

2

High-throughput

0.437

High

739538

RPA12
DNA-directed RNA polymerase I subunit RPA12

1

1

High-throughput

0.437

High

785938

LONM
Lon protease homolog, mitochondrial

1

1

High-throughput

0.437

High

864296

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.437

High

864305

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.437

High

444858

SIR3
Regulatory protein SIR3

1

0

High-throughput

0.426

High

649985

SIN3
Transcriptional regulatory protein SIN3

1

0

High-throughput

0.426

High

805553

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

0

High-throughput

0.426

High

864341

ESA1
Histone acetyltransferase ESA1

1

0

High-throughput

0.426

High

381156

H2B1
Histone H2B.1

1

1

High-throughput

0.407

High

488968

SWI6
Regulatory protein SWI6

1

2

High-throughput

0.407

High

545391

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.407

High

671536

SWI4
Regulatory protein SWI4

1

2

High-throughput

0.407

High

727144

HS104
Heat shock protein 104

1

1

High-throughput

0.407

High

736674

ASF1
Histone chaperone ASF1

1

1

High-throughput

0.407

High

737638

HIR1
Protein HIR1

1

2

High-throughput

0.407

High

738755

CBF3A
Centromere DNA-binding protein complex CBF3 subunit A

1

1

High-throughput

0.407

High

741872

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.407

High

752443

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

754163

MSN2
Zinc finger protein MSN2

1

1

High-throughput

0.407

High

754219

MSN4
Zinc finger protein MSN4

1

1

High-throughput

0.407

High

757572

YOX1
Homeobox protein YOX1

1

1

High-throughput

0.407

High

781761

SET3
SET domain-containing protein 3

1

2

High-throughput

0.407

High

813337

MBP1
Transcription factor MBP1

1

2

High-throughput

0.407

High

864299

HOS2
Probable histone deacetylase HOS2

1

1

High-throughput

0.407

High

864314

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

1

High-throughput

0.407

High

864318

HOS3
Histone deacetylase HOS3

1

2

High-throughput

0.407

High

864325

YHP1
Homeobox protein YHP1

1

1

High-throughput

0.407

High

864351

CAF1A
Chromatin assembly factor 1 subunit A

1

1

High-throughput

0.407

High

645949

DBF2
Cell cycle protein kinase DBF2

4

0

Small-scale

0.361

High

864312

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

2

0

High-throughput

0.313

High

864343

NUR1
Nuclear rim protein 1

2

0

Small-scale

0.305

High

419792

H2A2
Histone H2A.2

2

0

High-throughput

0.298

High

864320

GCN5
Histone acetyltransferase GCN5

2

0

High-throughput

0.288

High

632273

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.282

High

365788

KTHY
Thymidylate kinase

1

0

High-throughput

0.279

Low

448757

SNF1
Carbon catabolite-derepressing protein kinase

1

0

High-throughput

0.279

Low

452744

ADR1
Regulatory protein ADR1

1

0

High-throughput

0.279

Low

464615

PBS2
MAP kinase kinase PBS2

1

0

High-throughput

0.279

Low

642416

MCK1
Protein kinase MCK1

1

0

High-throughput

0.279

Low

676651

SGF29
SAGA complex subunit SGF29

1

0

High-throughput

0.279

Low

709850

BMH1
Protein BMH1

1

0

High-throughput

0.279

Low

722053

XPO1
Exportin-1

1

0

High-throughput

0.279

Low

793944

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

0

High-throughput

0.279

Low

804813

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

0

High-throughput

0.279

Low

824986

FKH1
Fork head protein homolog 1

1

0

High-throughput

0.279

Low

844361

YCH1
CDC25-like phosphatase YCH1

1

0

High-throughput

0.279

Low

864303

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.279

Low

864313

KAPS
Adenylyl-sulfate kinase

1

0

High-throughput

0.279

Low

864338

PSR2
Probable phosphatase PSR2

1

0

High-throughput

0.279

Low

864345

RTK1
Probable serine/threonine-protein kinase RTK1

1

0

High-throughput

0.279

Low

864319

GDE1
Glycerophosphocholine phosphodiesterase GDE1

1

0

High-throughput

0.269

Low

864333

CORO
Coronin-like protein

1

0

High-throughput

0.269

Low

864346

DCS2
Inactive diphosphatase DCS2

1

0

High-throughput

0.269

Low

649642

KCC2
Calcium/calmodulin-dependent protein kinase II

1

0

High-throughput

0.261

Low

758112

CASP
Protein CASP

1

0

High-throughput

0.251

Low

864335

HDA2
HDA1 complex subunit 2

1

0

High-throughput

0.251

Low

448315

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

0

High-throughput

0.249

Low

458583

SEC4
Ras-related protein SEC4

1

0

Small-scale

0.249

Low

632182

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.249

Low

645072

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

0

High-throughput

0.249

Low

693499

CBPS
Carboxypeptidase S

1

0

High-throughput

0.249

Low

735049

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.249

Low

745798

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.249

Low

748454

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

800661

KPR2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.249

Low

808849

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.249

Low

812442

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

815823

BEM2
GTPase-activating protein BEM2/IPL2

1

0

High-throughput

0.249

Low

864304

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

Small-scale

0.249

Low

864310

REG1
Resistance to glucose repression protein 1

1

0

High-throughput

0.249

Low

864334

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.249

Low

864337

IWR1
RNA polymerase II nuclear localization protein IWR1

1

0

High-throughput

0.249

Low

864342

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

864344

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.249

Low

64256

YP010
UPF0495 protein YPR010C-A

1

0

High-throughput

0.232

Low

448189

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.232

Low

548782

MCM1
Pheromone receptor transcription factor

1

0

High-throughput

0.232

Low

575965

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.232

Low

645618

AFT1
Iron-regulated transcriptional activator AFT1

1

0

High-throughput

0.232

Low

713278

MCM5
Minichromosome maintenance protein 5

1

0

High-throughput

0.232

Low

736520

SFP1
Transcription factor SFP1

1

0

High-throughput

0.232

Low

737413

FKBP2
Peptidyl-prolyl cis-trans isomerase FPR2

1

0

High-throughput

0.232

Low

739679

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.232

Low

745481

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

1

0

High-throughput

0.232

Low

746335

RGT1
Glucose transport transcription regulator RGT1

1

0

High-throughput

0.232

Low

781147

SWD2
COMPASS component SWD2

1

0

High-throughput

0.232

Low

820422

RT106
Histone chaperone RTT106

1

0

High-throughput

0.232

Low

835520

AZF1
Transcription factor AZF1

1

0

High-throughput

0.232

Low

844385

SERB
Phosphoserine phosphatase

1

0

High-throughput

0.232

Low

858378

STU2
Protein STU2

1

0

High-throughput

0.232

Low

858434

TAF1
Transcription initiation factor TFIID subunit 1

1

0

High-throughput

0.232

Low

864298

SPT20
SAGA complex subunit SPT20

1

0

High-throughput

0.232

Low

864306

MOT3
Transcriptional activator/repressor MOT3

1

0

High-throughput

0.232

Low

864307

H3
Histone H3

1

0

High-throughput

0.232

Low

864322

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.232

Low

864327

POB3
FACT complex subunit POB3

1

0

High-throughput

0.232

Low

864328

RCO1
Transcriptional regulatory protein RCO1

1

0

High-throughput

0.232

Low

864329

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

0

High-throughput

0.232

Low

864330

SWR1
Helicase SWR1

1

0

High-throughput

0.232

Low

864336

BRE1
E3 ubiquitin-protein ligase BRE1

1

0

High-throughput

0.232

Low

864339

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025