HitPredict

Interactor 1: AP3D1 (O14617)
AP-3 complex subunit delta-1 (AP-3 complex subunit delta) (Adaptor-related protein complex 3 subunit delta-1) (Delta-adaptin)
Gene: AP3D1

Interactor 2: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29467282, 17353931
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1153 Hs			1 454
+	Hs
		212581 AP1G1_HUMAN (17-836): 0: 595: 18.83		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		346462 AP2B1_HUMAN (37-965): 0: 580: 14.83		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		348382 COPG1_HUMAN (32-869): 5.38e-174: 536: 12.63		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		348131 COPG2_HUMAN (32-869): 1.56e-172: 532: 12.76		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		276352 AP1G2_HUMAN (18-767): 3.19e-169: 521: 17.16		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		302080 AP2A2_HUMAN (16-652): 7.04e-149: 472: 19.68		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		321453 AP2A1_HUMAN (16-729): 3.6e-148: 471: 18.78		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		379252 AP2B1_HUMAN (37-965): 0: 580: 14.83		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40