Protein: THP2
THO complex subunit THP2

Gene: THP2
Organism: Saccharomyces cerevisiae S288C
Interactions: 79
UniProt ID: O13539

Gene Ontology (top 5):
GO:0000346 - transcription export complex
GO:0000347 - THO complex
GO:0000445 - THO complex part of transcription export complex
GO:0000446 - nucleoplasmic THO complex
GO:0003676 - nucleic acid binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

150149

HPR1
THO complex subunit HPR1

13

0

Small-scale

0.929

High

150183

THO2
THO complex subunit 2

11

0

Small-scale

0.926

High

150159

MFT1
THO complex subunit MFT1

10

0

Small-scale

0.923

High

150190

SUB2
ATP-dependent RNA helicase SUB2

5

0

Small-scale

0.684

High

150152

GBP2
Serine/arginine

7

2

Small-scale

0.680

High

150184

TEX1
Protein TEX1

4

0

Small-scale

0.657

High

150195

YRA1
RNA annealing protein YRA1

3

1

Small-scale

0.650

High

150167

HRB1
Serine/arginine

4

1

Small-scale

0.630

High

150193

NCBP2
Nuclear cap-binding protein subunit 2

3

0

Small-scale

0.613

High

150122

THP2
THO complex subunit THP2

2

0

High-throughput

0.559

High

150198

MEX67
mRNA export factor MEX67

2

0

Small-scale

0.559

High

150173

SSB2
Ribosome-associated molecular chaperone SSB2

2

1

High-throughput

0.504

High

150147

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

Small-scale

0.458

High

150161

NCBP1
Nuclear cap-binding protein complex subunit 1

1

0

High-throughput

0.458

High

150166

YHS7
Uncharacterized protein YHR127W

1

0

High-throughput

0.458

High

150174

MLP2
Protein MLP2

1

0

High-throughput

0.458

High

150145

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

1

High-throughput

0.437

High

150150

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

1

1

High-throughput

0.437

High

150187

NOP3
Serine/arginine

1

2

High-throughput

0.437

High

150135

HSP73
Heat shock protein SSA3

1

2

High-throughput

0.407

High

150141

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.407

High

150142

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.407

High

150154

RL8B
Large ribosomal subunit protein eL8B

1

0

High-throughput

0.279

Low

150156

RPN2
26S proteasome regulatory subunit RPN2

1

0

High-throughput

0.279

Low

150164

OLA1
Obg-like ATPase 1

1

0

High-throughput

0.279

Low

150181

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

0

High-throughput

0.279

Low

150177

CYP7
Peptidyl-prolyl cis-trans isomerase CYP7

1

0

High-throughput

0.269

Low

150176

RPC9
DNA-directed RNA polymerase III subunit RPC9

1

0

High-throughput

0.265

Low

150186

COG6
Conserved oligomeric Golgi complex subunit 6

1

0

High-throughput

0.265

Low

150189

ATG17
Autophagy-related protein 17

1

0

High-throughput

0.265

Low

150194

MED2
Mediator of RNA polymerase II transcription subunit 2

1

0

High-throughput

0.265

Low

150172

SPC25
Kinetochore protein SPC25

1

0

High-throughput

0.251

Low

150196

CENPH
Inner kinetochore subunit MCM16

1

0

High-throughput

0.251

Low

149436

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.249

Low

150127

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

150128

H2A2
Histone H2A.2

1

0

High-throughput

0.249

Low

150130

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

150131

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.249

Low

150132

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.249

Low

150133

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

150134

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

150136

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

150137

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

150138

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

150139

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

150140

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

150144

CBP7
Cytochrome B translational activator CBS2

1

0

High-throughput

0.249

Low

150151

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.249

Low

150153

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

150155

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

0

High-throughput

0.249

Low

150157

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

150160

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

150162

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

150163

YRA2
RNA annealing protein YRA2

1

0

High-throughput

0.249

Low

150165

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

150170

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

150179

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

150185

YNO0
Uncharacterized protein YNL140C

1

0

High-throughput

0.249

Low

150188

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

150191

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

150197

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.249

Low

150182

TAM41
Phosphatidate cytidylyltransferase, mitochondrial

1

0

High-throughput

0.238

Low

150192

SOG2
Leucine-rich repeat-containing protein SOG2

1

0

High-throughput

0.238

Low

150123

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.232

Low

150124

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.232

Low

150125

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low

150126

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.232

Low

150129

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.232

Low

150143

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.232

Low

150146

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low

150148

EF3A
Elongation factor 3A

1

0

High-throughput

0.232

Low

150158

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

150168

TCPD
T-complex protein 1 subunit delta

1

0

High-throughput

0.232

Low

150169

CAJ1
Protein CAJ1

1

0

High-throughput

0.232

Low

150171

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.232

Low

150175

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low

150178

HLJ1
Protein HLJ1

1

0

High-throughput

0.232

Low

150180

RL4B
Large ribosomal subunit protein uL4B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025