HitPredict

Interactor 1: ENC1 (O14682)
Ectoderm-neural cortex protein 1 (ENC-1) (Kelch-like protein 37) (Nuclear matrix protein NRP/B) (p53-induced gene 10 protein)
Gene: ENC1

Interactor 2: RBX1 (P62877)
E3 ubiquitin-protein ligase RBX1 (EC 2.3.2.27) (EC 2.3.2.32) (E3 ubiquitin-protein transferase RBX1) (Protein ZYP) (RING finger protein 75) (RING-box protein 1) (Rbx1) (Regulator of cullins 1) (ROC1) [Cleaved into: E3 ubiquitin-protein ligase RBX1, N-terminally processed (E3 ubiquitin-protein transferase RBX1, N-terminally processed)]
Gene: RBX1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15983046
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016567 - protein ubiquitination GO:0031463 - Cul3-RING ubiquitin ligase complex
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 589 Hs			1 108
+	Hs
		921335 KLHL7_HUMAN (36-526): 3.53e-61: 214: 27.89		RBX1_HUMAN (1-108): 5.69e-51: 157: 100.00
+	Hs
		921260 KEAP1_HUMAN (386-589): 1.53e-48: 180: 22.12		RBX1_HUMAN (1-108): 5.69e-51: 157: 100.00
+	Hs
		299513 KLH18_HUMAN (425-588): 5.52e-43: 164: 21.69		RBX1_HUMAN (1-108): 5.69e-51: 157: 100.00
+	Hs
		921464 KLHL3_HUMAN (440-589): 6.52e-35: 141: 19.21		RBX1_HUMAN (1-108): 5.69e-51: 157: 100.00
+	Hs
		921308 KLH24_HUMAN (373-588): 6.23e-29: 123: 20.64		RBX1_HUMAN (1-108): 5.69e-51: 157: 100.00
+	Hs
		921453 KLHL8_HUMAN (271-443): 2.76e-24: 109: 18.86		RBX1_HUMAN (1-108): 5.69e-51: 157: 100.00
+	Hs
		921456 KLH13_HUMAN (505-589): 1.71e-15: 81.8: 18.89		RBX1_HUMAN (1-108): 5.69e-51: 157: 100.00
+	Hs
		921454 KLHL9_HUMAN (505-589): 2.81e-15: 81: 20.00		RBX1_HUMAN (1-108): 5.69e-51: 157: 100.00