HitPredict

Interactor 1: KMT2D (O14686)
Histone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.364) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2)
Gene: KMT2D

Interactor 2: GSC (P56915)
Homeobox protein goosecoid
Gene: GSC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38297188
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 5537 Hs			1 257
+	Hs
		152592 KMT2D_HUMAN (1-5537): 0: 1986: 100.00		PAX6_HUMAN (118-242): 1.4e-41: 149: 39.39
+	Hs
		152588 KMT2D_HUMAN (1-5537): 0: 1986: 100.00		PAX7_HUMAN (158-218): 4.7e-16: 79: 59.02
+	Hs
		641566 EHMT1_HUMAN (4886-5533): 1.11e-113: 399: 15.17		PAX6_HUMAN (118-242): 1.4e-41: 149: 39.39
+	Hs
		641528 EHMT2_HUMAN (4886-5533): 3.48e-114: 398: 17.77		PAX6_HUMAN (118-242): 1.4e-41: 149: 39.39
+	Hs
		1334136 EHMT1_HUMAN (4886-5533): 1.11e-113: 399: 15.17		VSX1_HUMAN (39-230): 8.41e-30: 116: 31.96
+	Hs
		1296426 EHMT2_HUMAN (4886-5533): 3.48e-114: 398: 17.77		VSX1_HUMAN (39-230): 8.41e-30: 116: 31.96
+	Hs
		595604 EZH2_HUMAN (5194-5519): 5.62e-91: 317: 18.91		HXA5_HUMAN (63-231): 5.08e-32: 120: 19.65
+	Hs
		882142 KMT2C_HUMAN (223-338): 3.09e-09: 66.3: 40.34		GSC_HUMAN (1-257): 2.5e-64: 203: 100.00
+	Dm
		1359818 Q9W1H0_DROME (198-353): 4.05e-25: 118: 26.38		Q9V490_DROME (137-257): 6.15e-34: 130: 30.89
+	Hs
		641503 DPF1_HUMAN (240-320): 4.65e-15: 82.8: 46.43		PAX6_HUMAN (118-242): 1.4e-41: 149: 39.39
+	Hs
		641482 KMT2C_HUMAN (223-338): 3.09e-09: 66.3: 40.34		PAX6_HUMAN (118-242): 1.4e-41: 149: 39.39
+	Hs
		1300555 SETD2_HUMAN (5389-5536): 1.87e-15: 87: 34.23		ARX_HUMAN (99-238): 1.57e-32: 126: 31.92
+	Dm
		950008 Q7K3G5_DROME (240-320): 6.24e-15: 83.6: 42.86		UBX_DROME (28-221): 3.13e-30: 118: 17.62
+	Dm
		1179567 Q7K3G5_DROME (240-320): 6.24e-15: 83.6: 42.86		Q9XZU0_DROME (152-257): 1.15e-28: 113: 33.91
+	Dm
		1179548 Q7K3G5_DROME (240-320): 6.24e-15: 83.6: 42.86		Q8T0V5_DROME (152-257): 2.05e-28: 112: 33.91
+	Hs
		620184 DPF1_HUMAN (240-320): 4.65e-15: 82.8: 46.43		PAX7_HUMAN (158-218): 4.7e-16: 79: 59.02
+	Hs
		620175 KMT2C_HUMAN (223-338): 3.09e-09: 66.3: 40.34		PAX7_HUMAN (158-218): 4.7e-16: 79: 59.02