HitPredict

Interactor 1: ITBP1 (O14713)
Integrin beta-1-binding protein 1 (Integrin cytoplasmic domain-associated protein 1) (ICAP-1)
Gene: ITGB1BP1

Interactor 2: ITB1 (P05556)
Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)
Gene: ITGB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.55	0.665

The method score is based on:

Property	Details
Experiments	28049720, 9281591, 11741908, 11919189
Identification Methods	pull down, affinity chromatography technology, two hybrid
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001726 - ruffle GO:0005178 - integrin binding GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0007160 - cell-matrix adhesion and 7 others more... GO:0007229 - integrin-mediated signaling pathway GO:0016020 - membrane GO:0016477 - cell migration GO:0019901 - protein kinase binding GO:0030027 - lamellipodium GO:0048471 - perinuclear region of cytoplasm GO:0051897 - positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
Homologous interactions	0

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Last updated: 15 Jul 2024