Interactor 1: NHRF1 (O14745)
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF-1) (Ezrin-radixin-moesin-binding phosphoprotein 50) (EBP50) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory factor 1)
Gene: NHERF1
Interactor 2: EZRI (P15311)
Ezrin (Cytovillin) (Villin-2) (p81)
Gene: EZR
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.965 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 29568061, 23414517, 34079125, 11684085, 9314537, 20937695, 15020681, 11285285 |
| Identification Methods | proximity labelling technology, two hybrid, pull down, affinity chromatography technology, two hybrid fragment pooling approach |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | EBP50_C~FERM_C |
| Common GO terms | GO:0001726 - ruffle GO:0005737 - cytoplasm GO:0005902 - microvillus GO:0008360 - regulation of cell shape GO:0015629 - actin cytoskeleton and 12 others more... |
| Homologous interactions | 19 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
