HitPredict

Interactor 1: NHRF1 (O14745)
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF-1) (Ezrin-radixin-moesin-binding phosphoprotein 50) (EBP50) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory factor 1)
Gene: NHERF1

Interactor 2: EPHB1 (P54762)
Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase 2) (EPH-like kinase 6) (EK6) (hEK6) (Neuronally-expressed EPH-related tyrosine kinase) (NET) (Tyrosine-protein kinase receptor EPH-2)
Gene: EPHB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	23118026
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~fn3, PDZ~SAM_1
Common GO terms	GO:0044877 - protein-containing complex binding GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 358 Hs			1 984
+	Hs
		153921 NHRF1_HUMAN (1-358): 2.51e-82: 256: 100.00		EPHA7_HUMAN (1-981): 0: 1151: 56.96
+	Hs
		665600 SCRIB_HUMAN (7-337): 1.45e-29: 122: 19.83		EPHB2_HUMAN (19-981): 0: 1198: 73.76
+	Hs
		1049958 SCRIB_HUMAN (7-337): 1.45e-29: 122: 19.83		EPHA7_HUMAN (1-981): 0: 1151: 56.96
+	Hs
		665589 PTN13_HUMAN (71-237): 3.87e-12: 69.7: 12.97		EPHB2_HUMAN (19-981): 0: 1198: 73.76
+	Hs
		1072546 LNX2_HUMAN (4-348): 1.22e-27: 115: 14.33		EPHA7_HUMAN (1-981): 0: 1151: 56.96
+	Hs
		1021499 DLG1_HUMAN (55-238): 9.08e-13: 71.6: 18.85		EPHA7_HUMAN (1-981): 0: 1151: 56.96
+	Hs
		872639 DLG1_HUMAN (55-238): 9.08e-13: 71.6: 18.85		EPHA4_HUMAN (13-983): 0: 1150: 59.10
+	Hs
		1020163 PTN13_HUMAN (71-237): 3.87e-12: 69.7: 12.97		EPHA7_HUMAN (1-981): 0: 1151: 56.96
+	Hs
		872638 PTN13_HUMAN (71-237): 3.87e-12: 69.7: 12.97		EPHA4_HUMAN (13-983): 0: 1150: 59.10
+	Hs
		872433 DLG1_HUMAN (55-238): 9.08e-13: 71.6: 18.85		EPHA5_HUMAN (1-981): 0: 1143: 55.78
+	Hs
		872431 PTN13_HUMAN (71-237): 3.87e-12: 69.7: 12.97		EPHA5_HUMAN (1-981): 0: 1143: 55.78
+	Hs
		665393 PTN13_HUMAN (71-237): 3.87e-12: 69.7: 12.97		EPHA3_HUMAN (14-981): 0: 1131: 55.67
+	Hs
		665228 PTN13_HUMAN (71-237): 3.87e-12: 69.7: 12.97		EPHA2_HUMAN (17-978): 0: 1032: 46.58
+	Hs
		600564 PTN13_HUMAN (71-237): 3.87e-12: 69.7: 12.97		EPHA1_HUMAN (11-973): 0: 955: 41.76
+	Hs
		153881 NHRF1_HUMAN (1-358): 2.51e-82: 256: 100.00		UFO_HUMAN (131-963): 1.83e-174: 532: 23.30
+	Hs
		674422 SCRIB_HUMAN (7-337): 1.45e-29: 122: 19.83		UFO_HUMAN (131-963): 1.83e-174: 532: 23.30
+	Hs
		674412 DLG1_HUMAN (55-238): 9.08e-13: 71.6: 18.85		UFO_HUMAN (131-963): 1.83e-174: 532: 23.30
+	Hs
		435639 SCRIB_HUMAN (7-337): 1.45e-29: 122: 19.83		IGF1R_HUMAN (390-883): 2.15e-141: 458: 30.71
+	Hs
		412128 DLG4_HUMAN (88-235): 4.14e-14: 75.5: 19.36		FYN_HUMAN (613-879): 2.52e-64: 228: 42.54
+	Mm
		411930 DLG1_MOUSE (56-238): 5.01e-13: 72.4: 19.37		LCK_MOUSE (577-879): 1.39e-64: 228: 41.12