HitPredict

Interactor 1: MEIS2 (O14770)
Homeobox protein Meis2 (Meis1-related protein 1)
Gene: MEIS2

Interactor 2: TLX1 (P31314)
T-cell leukemia homeobox protein 1 (Homeobox protein Hox-11) (Proto-oncogene TCL-3) (T-cell leukemia/lymphoma protein 3)
Gene: TLX1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.783

The method score is based on:

Property Details
Experiments 16357834, 19559479
Identification Methods pull down, two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Homeobox_KN~Homeodomain
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005634 - nucleus
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 477
Hs

1 330
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024