Interactor 1: MEIS2 (O14770)
Homeobox protein Meis2 (Meis1-related protein 1)
Gene: MEIS2

Interactor 2: PBX1 (P40424)
Pre-B-cell leukemia transcription factor 1 (Homeobox protein PBX1) (Homeobox protein PRL)
Gene: PBX1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.970

The method score is based on:

Property Details
Experiments 26186194, 28514442, 32296183, 33961781, 20211142, 11279116, unassigned1304, 20553494
Identification Methods affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Homeobox_KN~Homeobox_KN
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001654 - eye development
and 6 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 477
Hs

1 430
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Last updated: 15 Jul 2024