Protein: KIRR1
Kin of IRRE-like protein 1 (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1)

Gene: KIRR1, KIRREL1
Organism: Homo sapiens
Interactions: 147
UniProt ID: Q96J84

Gene Ontology (top 5):
GO:0003094 - glomerular filtration
GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0017022 - myosin binding
GO:0030838 - positive regulation of actin filament polymerization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

627557

DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain

2

4

High-throughput

0.789

High

821757

CD79B
B-cell antigen receptor complex-associated protein beta chain

2

0

High-throughput

0.770

High

249934

NPHN
Nephrin

2

19

Small-scale

0.754

High

1116835

AVR2B
Activin receptor type-2B

1

3

High-throughput

0.691

High

1058914

ZO1
Tight junction protein 1

3

9

Small-scale

0.686

High

349205

LATS1
Serine/threonine-protein kinase LATS1

2

4

High-throughput

0.675

High

732939

GASR
Gastrin/cholecystokinin type B receptor

3

1

High-throughput

0.662

High

1350588

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

3

1

High-throughput

0.662

High

375842

RASK
GTPase KRas

3

20

High-throughput

0.640

High

1394680

ANTR1
Anthrax toxin receptor 1

3

0

High-throughput

0.638

High

669241

NK1R
Substance-P receptor

2

3

High-throughput

0.628

High

1128940

I13R2
Interleukin-13 receptor subunit alpha-2

2

8

High-throughput

0.628

High

909136

NEK4
Serine/threonine-protein kinase Nek4

1

2

High-throughput

0.618

High

1331597

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

1

4

High-throughput

0.618

High

710428

EPHA2
Ephrin type-A receptor 2

1

13

High-throughput

0.618

High

774557

BASI
Basigin

1

19

High-throughput

0.618

High

787233

BMR1A
Bone morphogenetic protein receptor type-1A

1

3

High-throughput

0.618

High

845757

MUC18
Cell surface glycoprotein MUC18

1

20

High-throughput

0.618

High

1004162

CXAR
Coxsackievirus and adenovirus receptor

1

18

High-throughput

0.618

High

1147408

EPHA7
Ephrin type-A receptor 7

1

11

High-throughput

0.618

High

1394670

KIRR1
Kin of IRRE-like protein 1

1

20

Small-scale

0.618

High

1394692

ALK
ALK tyrosine kinase receptor

1

8

High-throughput

0.618

High

1356475

TB22A
TBC1 domain family member 22A

3

1

High-throughput

0.609

High

1187215

CC50B
Cell cycle control protein 50B

2

0

High-throughput

0.602

High

374138

RASN
GTPase NRas

2

20

High-throughput

0.584

High

975177

ARF6
ADP-ribosylation factor 6

2

4

High-throughput

0.584

High

978226

RHOB
Rho-related GTP-binding protein RhoB

2

17

High-throughput

0.584

High

1101877

SKP2
S-phase kinase-associated protein 2

2

1

High-throughput

0.574

High

1235382

KLH10
Kelch-like protein 10

2

5

High-throughput

0.574

High

1361077

CBPA5
Carboxypeptidase A5

2

2

High-throughput

0.574

High

1146455

KS6A2
Ribosomal protein S6 kinase alpha-2

1

2

High-throughput

0.553

High

848550

MAGA8
Melanoma-associated antigen 8

2

3

High-throughput

0.549

High

622666

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

0

High-throughput

0.546

High

1254272

UBR3
E3 ubiquitin-protein ligase UBR3

2

1

High-throughput

0.537

High

406923

MAS
Proto-oncogene Mas

1

4

High-throughput

0.536

High

711583

NK3R
Neuromedin-K receptor

1

3

High-throughput

0.536

High

761281

RYK
Tyrosine-protein kinase RYK

1

14

High-throughput

0.536

High

880186

PTH2R
Parathyroid hormone 2 receptor

1

2

High-throughput

0.536

High

987864

GRB2
Growth factor receptor-bound protein 2

1

14

High-throughput

0.536

High

1168747

DOXA2
Dual oxidase maturation factor 2

1

1

High-throughput

0.536

High

1394683

PICK1
PRKCA-binding protein

1

1

High-throughput

0.536

High

1394685

GPC5B
G-protein coupled receptor family C group 5 member B

1

1

High-throughput

0.536

High

1394693

CLC4A
C-type lectin domain family 4 member A

1

4

High-throughput

0.536

High

976484

RB11A
Ras-related protein Rab-11A

2

3

High-throughput

0.533

High

139291

UPK2
Uroplakin-2

1

0

High-throughput

0.513

High

986912

CCG7
Voltage-dependent calcium channel gamma-7 subunit

1

0

High-throughput

0.513

High

1363206

AQP3
Aquaporin-3

1

0

High-throughput

0.513

High

1394690

TRHDE
Thyrotropin-releasing hormone-degrading ectoenzyme

1

0

High-throughput

0.513

High

1394675

S17A9
Voltage-gated purine nucleotide uniporter SLC17A9

1

0

High-throughput

0.481

High

126745

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

189775

STX7
Syntaxin-7

1

4

High-throughput

0.479

High

218630

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.479

High

299332

FLOT1
Flotillin-1

1

5

High-throughput

0.479

High

341125

DIRA3
GTP-binding protein Di-Ras3

1

3

High-throughput

0.479

High

363714

EGFR
Epidermal growth factor receptor

1

14

High-throughput

0.479

High

374855

RASH
GTPase HRas

1

15

High-throughput

0.479

High

411001

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

11

High-throughput

0.479

High

463707

LYN
Tyrosine-protein kinase Lyn

1

9

High-throughput

0.479

High

466411

RHOC
Rho-related GTP-binding protein RhoC

1

14

High-throughput

0.479

High

581232

RAC2
Ras-related C3 botulinum toxin substrate 2

1

12

High-throughput

0.479

High

601405

RHOQ
Rho-related GTP-binding protein RhoQ

1

18

High-throughput

0.479

High

604154

CXA1
Gap junction alpha-1 protein

1

5

High-throughput

0.479

High

630931

RAB4A
Ras-related protein Rab-4A

1

6

High-throughput

0.479

High

631410

RAB5A
Ras-related protein Rab-5A

1

5

High-throughput

0.479

High

715722

MARCS
Myristoylated alanine-rich C-kinase substrate

1

5

High-throughput

0.479

High

900988

RAB5C
Ras-related protein Rab-5C

1

5

High-throughput

0.479

High

910165

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.479

High

936411

AFAD
Afadin

1

13

High-throughput

0.479

High

941829

ARL4C
ADP-ribosylation factor-like protein 4C

1

17

High-throughput

0.479

High

945069

RAB25
Ras-related protein Rab-25

1

4

High-throughput

0.479

High

953618

RAC3
Ras-related C3 botulinum toxin substrate 3

1

14

High-throughput

0.479

High

955477

CDC42
Cell division control protein 42 homolog

1

16

High-throughput

0.479

High

962384

RHOA
Transforming protein RhoA

1

15

High-throughput

0.479

High

962807

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.479

High

988611

RAC1
Ras-related C3 botulinum toxin substrate 1

1

14

High-throughput

0.479

High

1015683

RHOG
Rho-related GTP-binding protein RhoG

1

12

High-throughput

0.479

High

1041229

CAV1
Caveolin-1

1

2

High-throughput

0.479

High

1087242

STX4
Syntaxin-4

1

4

High-throughput

0.479

High

1145058

RAB35
Ras-related protein Rab-35

1

5

High-throughput

0.479

High

1151821

RHOH
Rho-related GTP-binding protein RhoH

1

18

High-throughput

0.479

High

1159802

OCLN
Occludin

1

2

High-throughput

0.479

High

1229037

RNF43
E3 ubiquitin-protein ligase RNF43

1

2

High-throughput

0.479

High

1233416

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

1270948

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

1322945

CXD3
Gap junction delta-3 protein

1

5

High-throughput

0.479

High

1326505

ARL14
ADP-ribosylation factor-like protein 14

1

9

High-throughput

0.479

High

1353243

PARD3
Partitioning defective 3 homolog

1

14

High-throughput

0.479

High

1366863

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.479

High

1380900

ARL11
ADP-ribosylation factor-like protein 11

1

17

High-throughput

0.479

High

1394671

RHOV
Rho-related GTP-binding protein RhoV

1

16

High-throughput

0.479

High

1394674

CAB45
45 kDa calcium-binding protein

1

1

High-throughput

0.479

High

1394677

DNJC5
DnaJ homolog subfamily C member 5

1

4

High-throughput

0.479

High

1394679

RHOJ
Rho-related GTP-binding protein RhoJ

1

18

High-throughput

0.479

High

1394681

RHOF
Rho-related GTP-binding protein RhoF

1

18

High-throughput

0.479

High

1394691

MYO6
Unconventional myosin-VI

1

2

High-throughput

0.479

High

1220503

BTBD8
BTB/POZ domain-containing protein 8

1

11

High-throughput

0.470

High

154504

CLD4
Claudin-4

1

0

Small-scale

0.458

High

248043

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

540622

LAMP1
Lysosome-associated membrane glycoprotein 1

1

0

High-throughput

0.458

High

1249119

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1293282

LSR
Lipolysis-stimulated lipoprotein receptor

1

1

High-throughput

0.445

High

1310922

ZNT8
Proton-coupled zinc antiporter SLC30A8

1

5

High-throughput

0.445

High

1323749

S39AB
Zinc transporter ZIP11

1

4

High-throughput

0.445

High

1390862

ASIC4
Acid-sensing ion channel 4

1

2

High-throughput

0.445

High

1394673

ZNT3
Probable proton-coupled zinc antiporter SLC30A3

1

5

High-throughput

0.445

High

1394676

EHD4
EH domain-containing protein 4

1

1

High-throughput

0.445

High

1394684

S22AB
Solute carrier family 22 member 11

1

2

High-throughput

0.445

High

1394686

EHD3
EH domain-containing protein 3

1

1

High-throughput

0.445

High

1394689

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

1

1

High-throughput

0.445

High

1394694

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

2

High-throughput

0.445

High

139961

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

1

High-throughput

0.437

High

181725

CTDSL
CTD small phosphatase-like protein

1

1

High-throughput

0.437

High

327410

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.437

High

956447

RAB2A
Ras-related protein Rab-2A

1

6

High-throughput

0.437

High

1004973

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.437

High

1227262

A16L1
Autophagy-related protein 16-1

1

5

High-throughput

0.437

High

1381935

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.437

High

1394678

SAV1
Protein salvador homolog 1

1

10

High-throughput

0.437

High

1155091

UT2
Urea transporter 2

1

0

High-throughput

0.426

High

765803

BMI1
Polycomb complex protein BMI-1

1

2

High-throughput

0.407

High

1010091

DLK1
Protein delta homolog 1

1

18

High-throughput

0.407

High

1180405

KLH40
Kelch-like protein 40

1

7

High-throughput

0.407

High

1239534

ZNT6
Zinc transporter 6

1

5

High-throughput

0.407

High

1251885

CCNI2
Cyclin-I2

1

1

High-throughput

0.407

High

1259089

ILDR2
Immunoglobulin-like domain-containing receptor 2

1

1

High-throughput

0.407

High

1340502

DNJB8
DnaJ homolog subfamily B member 8

1

2

High-throughput

0.407

High

1394687

KLHL9
Kelch-like protein 9

1

5

High-throughput

0.407

High

1394688

KLH13
Kelch-like protein 13

1

5

High-throughput

0.407

High

1394672

ANM6
Protein arginine N-methyltransferase 6

3

0

High-throughput

0.347

High

1394682

SACA1
Sperm acrosome membrane-associated protein 1

3

0

High-throughput

0.347

High

289332

FCN3
Ficolin-3

1

0

High-throughput

0.279

Low

1022453

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.279

Low

1034799

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.279

Low

1206273

NHLC3
NHL repeat-containing protein 3

1

0

High-throughput

0.279

Low

1350860

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

703027

DPOD1
DNA polymerase delta catalytic subunit

1

0

High-throughput

0.249

Low

1289271

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

0

High-throughput

0.249

Low

1293111

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1357516

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.249

Low

922407

CRBB1
Beta-crystallin B1

1

0

High-throughput

0.232

Low

1064007

ECHP
Peroxisomal bifunctional enzyme

1

0

High-throughput

0.232

Low

1139025

SNX17
Sorting nexin-17

1

0

High-throughput

0.232

Low

1208130

S35D3
Solute carrier family 35 member D3

1

0

High-throughput

0.232

Low

1253922

FA83H
Protein FAM83H

1

0

High-throughput

0.232

Low

1258283

SAMC
Mitochondrial S-adenosylmethionine carrier protein

1

0

High-throughput

0.232

Low

1326030

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025