HitPredict

Interactor 1: TCRG1 (O14776)
Transcription elongation regulator 1 (TATA box-binding protein-associated factor 2S) (Transcription factor CA150)
Gene: TCERG1

Interactor 2: PIAS4 (Q8N2W9)
E3 SUMO-protein ligase PIAS4 (EC 2.3.2.27) (PIASy) (Protein inhibitor of activated STAT protein 4) (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma)
Gene: PIAS4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	15383276
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003712 - transcription coregulator activity GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1098 Hs			1 510
+	Hs
		263726 PR40A_HUMAN (342-1079): 1.36e-67: 247: 18.03		PIAS4_HUMAN (1-510): 0: 670: 100.00
+	Hs
		1056886 MDC1_HUMAN (24-892): 5.83e-33: 141: 9.38		PIAS4_HUMAN (1-510): 0: 670: 100.00
+	Hs
		263891 PR40A_HUMAN (342-1079): 1.36e-67: 247: 18.03		PIAS3_HUMAN (3-509): 0: 540: 46.59
+	Hs
		263454 PR40A_HUMAN (342-1079): 1.36e-67: 247: 18.03		PIAS1_HUMAN (3-508): 2.66e-180: 522: 46.42
+	Hs
		278083 MDC1_HUMAN (24-892): 5.83e-33: 141: 9.38		PIAS1_HUMAN (3-508): 2.66e-180: 522: 46.42