HitPredict

Interactor 1: NDC80 (O14777)
Kinetochore protein NDC80 homolog (Highly expressed in cancer protein) (Kinetochore protein Hec1) (HsHec1) (Kinetochore-associated protein 2) (Retinoblastoma-associated protein HEC)
Gene: NDC80

Interactor 2: PCNT (O95613)
Pericentrin (Kendrin) (Pericentrin-B)
Gene: PCNT

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol GO:0007052 - mitotic spindle organization GO:0016020 - membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 642 Hs			1 3336
+	Hs
		154949 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		CENPE_HUMAN (1328-3305): 2.89e-65: 250: 10.28
+	Hs
		155102 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		CP250_HUMAN (1630-3336): 3.41e-53: 210: 10.43
+	Hs
		154889 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		CE290_HUMAN (1764-3201): 5.48e-34: 147: 10.55
+	Hs
		155098 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		AKAP9_HUMAN (1605-3329): 1.28e-32: 142: 9.38
+	Hs
		155040 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		NIN_HUMAN (2297-3173): 3.07e-12: 75.5: 9.75
+	Hs
		724994 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		CP250_HUMAN (1630-3336): 3.41e-53: 210: 10.43
+	Mm
		93578 DESP_MOUSE (190-642): 1.18e-15: 83.5: 15.27		PLEC_MOUSE (2-1335): 1.57e-39: 165: 10.63
+	Hs
		724687 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		MYH10_HUMAN (2428-3327): 1.51e-34: 149: 10.93
+	Hs
		725097 MYH11_HUMAN (180-641): 3.92e-16: 84.8: 12.24		MYH10_HUMAN (2428-3327): 1.51e-34: 149: 10.93
+	Hs
		725095 MYH10_HUMAN (171-636): 1.34e-15: 83.3: 12.84		MYH10_HUMAN (2428-3327): 1.51e-34: 149: 10.93
+	Hs
		725002 UACA_HUMAN (191-641): 1.51e-30: 130: 13.88		MYH9_HUMAN (2690-3313): 1.18e-18: 96.7: 9.89
+	Hs
		1127269 TGO1_HUMAN (195-642): 2.07e-29: 127: 15.45		NIN_HUMAN (2297-3173): 3.07e-12: 75.5: 9.75
+	Dm
		114798 Q9VYB1_DROME (30-609): 1.5e-30: 129: 11.91		M9PD87_DROME (214-964): 7.73e-10: 67.6: 15.67
+	Hs
		724686 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		MYH9_HUMAN (2690-3313): 1.18e-18: 96.7: 9.89
+	Mm
		93570 DESP_MOUSE (190-642): 1.18e-15: 83.5: 15.27		MYH9_MOUSE (5-449): 6.13e-15: 84.4: 9.66
+	Hs
		724839 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		PLEC_HUMAN (2464-3115): 2.24e-12: 76.1: 14.83
+	Hs
		724895 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		MYH14_HUMAN (1365-1911): 6.08e-09: 64.6: 17.69
+	Hs
		725189 MYH10_HUMAN (171-636): 1.34e-15: 83.3: 12.84		MYH14_HUMAN (1365-1911): 6.08e-09: 64.6: 17.69