Protein: GDC
Solute carrier family 25 member 16 (Graves disease autoantigen) (GDA) (Graves disease carrier protein) (GDC) (Graves' didease protein) (hGP) (Mitochondrial solute carrier protein homolog)

Gene: GDC, SLC25A16
Organism: Homo sapiens
Interactions: 72
UniProt ID: P16260

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006839 - mitochondrial transport
GO:0015228 - coenzyme A transmembrane transporter activity
GO:0015297 - antiporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

593575

CD79B
B-cell antigen receptor complex-associated protein beta chain

2

7

High-throughput

0.726

High

593590

PDCD1
Programmed cell death protein 1

2

4

High-throughput

0.726

High

593570

DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain

3

11

High-throughput

0.609

High

593585

NRG1
Pro-neuregulin-1, membrane-bound isoform

3

2

High-throughput

0.609

High

593611

RN126
E3 ubiquitin-protein ligase RNF126

3

1

High-throughput

0.609

High

469456

SYPH
Synaptophysin

3

2

High-throughput

0.604

High

249922

NPHN
Nephrin

1

0

High-throughput

0.578

High

593605

S2544
Solute carrier family 25 member 44

1

15

High-throughput

0.575

High

163537

TPP1
Tripeptidyl-peptidase 1

2

1

High-throughput

0.574

High

273646

PP6R2
Serine/threonine-protein phosphatase 6 regulatory subunit 2

2

4

High-throughput

0.574

High

593596

F131B
Protein FAM131B

2

2

High-throughput

0.574

High

593612

EDEM2
ER degradation-enhancing alpha-mannosidase-like protein 2

2

1

High-throughput

0.574

High

593620

DKK3
Dickkopf-related protein 3

2

2

High-throughput

0.574

High

380255

DRA
HLA class II histocompatibility antigen, DR alpha chain

2

11

High-throughput

0.558

High

593607

CNDP1
Beta-Ala-His dipeptidase

2

1

High-throughput

0.558

High

258750

DNJA2
DnaJ homolog subfamily A member 2

2

5

High-throughput

0.549

High

593601

HUMMR
Protein MGARP

1

11

High-throughput

0.536

High

593615

IFG15
Torsin-1A-interacting protein 2, isoform IFRG15

2

2

High-throughput

0.533

High

593603

FAF2
FAS-associated factor 2

2

3

High-throughput

0.521

High

593623

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

6

High-throughput

0.514

High

593599

TOIP2
Torsin-1A-interacting protein 2

2

2

High-throughput

0.504

High

154796

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

1

6

High-throughput

0.489

High

182460

GP182
G-protein coupled receptor 182

1

20

High-throughput

0.489

High

260832

RAMP3
Receptor activity-modifying protein 3

1

6

High-throughput

0.489

High

593577

GPR12
G-protein coupled receptor 12

1

10

High-throughput

0.489

High

593582

IDD
Integral membrane protein DGCR2/IDD

1

5

High-throughput

0.489

High

593595

LRC55
Leucine-rich repeat-containing protein 55

1

6

High-throughput

0.489

High

593602

TICN2
Testican-2

1

1

High-throughput

0.489

High

593617

TSAP1
tRNA selenocysteine 1-associated protein 1

1

4

High-throughput

0.489

High

593624

CBPQ
Carboxypeptidase Q

1

1

High-throughput

0.489

High

317982

TOM70
Mitochondrial import receptor subunit TOM70

1

10

High-throughput

0.445

High

328495

NDUA7
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7

1

1

High-throughput

0.445

High

361998

AATM
Aspartate aminotransferase, mitochondrial

1

1

High-throughput

0.445

High

464243

FUMH
Fumarate hydratase, mitochondrial

1

1

High-throughput

0.445

High

593576

GPDM
Glycerol-3-phosphate dehydrogenase, mitochondrial

1

5

High-throughput

0.445

High

593578

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

1

1

High-throughput

0.445

High

593584

MMSA
Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial

1

1

High-throughput

0.445

High

593587

MPPA
Mitochondrial-processing peptidase subunit alpha

1

3

High-throughput

0.445

High

593591

ETFD
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial

1

1

High-throughput

0.445

High

593598

MCU
Calcium uniporter protein, mitochondrial

1

2

High-throughput

0.445

High

593609

ACON
Aconitate hydratase, mitochondrial

1

1

High-throughput

0.445

High

593621

KAD3
GTP:AMP phosphotransferase AK3, mitochondrial

1

2

High-throughput

0.445

High

593622

TRAK1
Trafficking kinesin-binding protein 1

1

6

High-throughput

0.445

High

593571

C4BPB
C4b-binding protein beta chain

1

1

High-throughput

0.437

High

593573

ITB8
Integrin beta-8

1

1

High-throughput

0.437

High

593593

RN123
E3 ubiquitin-protein ligase RNF123

1

1

High-throughput

0.437

High

593594

BAKOR
Beclin 1-associated autophagy-related key regulator

1

4

High-throughput

0.437

High

593606

TXD15
Thioredoxin domain-containing protein 15

1

5

High-throughput

0.437

High

593610

CAB45
45 kDa calcium-binding protein

1

6

High-throughput

0.437

High

333551

NDUC2
NADH dehydrogenase [ubiquinone] 1 subunit C2

1

0

High-throughput

0.426

High

593579

SCOT1
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial

1

0

High-throughput

0.426

High

593583

PYRD
Dihydroorotate dehydrogenase

1

0

High-throughput

0.426

High

593592

AL1L2
Mitochondrial 10-formyltetrahydrofolate dehydrogenase

1

0

High-throughput

0.426

High

593608

ATP5S
ATP synthase subunit s, mitochondrial

1

0

High-throughput

0.426

High

593614

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

0

High-throughput

0.426

High

593619

NDUF4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

1

0

High-throughput

0.426

High

593625

NDUB9
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9

1

0

High-throughput

0.426

High

51396

FSD2
Fibronectin type III and SPRY domain-containing protein 2

1

15

High-throughput

0.407

High

317313

ACL6B
Actin-like protein 6B

1

1

High-throughput

0.407

High

593572

ACKR3
Atypical chemokine receptor 3

1

16

High-throughput

0.407

High

593581

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

7

High-throughput

0.407

High

593588

TBB2A
Tubulin beta-2A chain

1

5

High-throughput

0.407

High

593589

KEAP1
Kelch-like ECH-associated protein 1

1

5

High-throughput

0.407

High

593597

S22AO
Steroid transmembrane transporter SLC22A24

1

9

High-throughput

0.407

High

593616

M1IP1
Mid1-interacting protein 1

1

1

High-throughput

0.407

High

593604

DTBP1
Dysbindin

1

0

High-throughput

0.249

Low

593574

GALNS
N-acetylgalactosamine-6-sulfatase

1

0

High-throughput

0.232

Low

593580

PSME3
Proteasome activator complex subunit 3

1

0

High-throughput

0.232

Low

593586

NUCB1
Nucleobindin-1

1

0

High-throughput

0.232

Low

593600

SETD6
N-lysine methyltransferase SETD6

1

0

High-throughput

0.232

Low

593613

CHIA
Acidic mammalian chitinase

1

0

High-throughput

0.232

Low

593618

MS18A
Protein Mis18-alpha

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025