HitPredict

Interactor 1: NDC80 (O14777)
Kinetochore protein NDC80 homolog (Highly expressed in cancer protein) (Kinetochore protein Hec1) (HsHec1) (Kinetochore-associated protein 2) (Retinoblastoma-associated protein HEC)
Gene: NDC80

Interactor 2: AMOT (Q4VCS5)
Angiomotin
Gene: AMOT

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	24981860, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 642 Hs			1 1084
+	Hs
		1118950 TGO1_HUMAN (195-642): 2.07e-29: 127: 15.45		AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00
+	Hs
		155159 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		CE164_HUMAN (20-1032): 2.66e-35: 148: 11.99
+	Hs
		155164 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		AMOL2_HUMAN (296-902): 3.42e-27: 121: 39.81
+	Hs
		155131 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		MYO5C_HUMAN (338-916): 1.21e-17: 91.1: 10.24
+	Hs
		154949 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		CENPE_HUMAN (376-768): 1.87e-12: 74.2: 19.49
+	Hs
		154959 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		DCTN1_HUMAN (510-863): 3.81e-09: 63.3: 14.85
+	Hs
		1137917 MRCKB_HUMAN (258-642): 1.73e-21: 102: 12.78		MRCKA_HUMAN (257-924): 1.39e-36: 152: 10.38
+	Hs
		1137871 MRCKA_HUMAN (140-627): 3.84e-19: 94.5: 11.42		MRCKA_HUMAN (257-924): 1.39e-36: 152: 10.38
+	Rn
		222472 MRCKA_RAT (181-627): 1.66e-21: 102: 10.82		MRCKA_RAT (432-960): 6.53e-29: 128: 13.95
+	Hs
		725002 UACA_HUMAN (191-641): 1.51e-30: 130: 13.88		MYH9_HUMAN (51-655): 1.51e-14: 81.1: 9.31
+	Rn
		222476 MRCKA_RAT (181-627): 1.66e-21: 102: 10.82		MRCKB_RAT (245-687): 6.55e-20: 98.5: 10.95
+	Rn
		1186812 MRCKB_RAT (266-642): 2.4e-19: 95.2: 10.61		MRCKB_RAT (245-687): 6.55e-20: 98.5: 10.95
+	Hs
		725035 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		MYO5C_HUMAN (338-916): 1.21e-17: 91.1: 10.24
+	Hs
		724686 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		MYH9_HUMAN (51-655): 1.51e-14: 81.1: 9.31
+	Hs
		148460 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		CTRO_HUMAN (533-815): 3.66e-12: 73.4: 12.37
+	Hs
		724687 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		MYH10_HUMAN (479-879): 3.84e-12: 73: 12.04
+	Hs
		148466 MYH11_HUMAN (180-641): 3.92e-16: 84.8: 12.24		CTRO_HUMAN (533-815): 3.66e-12: 73.4: 12.37
+	Hs
		725097 MYH11_HUMAN (180-641): 3.92e-16: 84.8: 12.24		MYH10_HUMAN (479-879): 3.84e-12: 73: 12.04