Interactor 1: NRP1 (O14786)
Neuropilin-1 (Vascular endothelial cell growth factor 165 receptor) (CD antigen CD304)
Gene: NRP1
Interactor 2: VEGFA (P15692)
Vascular endothelial growth factor A, long form (L-VEGF) (Vascular permeability factor) (VPF) [Cleaved into: N-VEGF; VEGFA]
Gene: VEGFA
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.986 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26804163, 18325345, 16423422, 21939755, 11886873, 30236477, 11986311, 9529250, 22318724, 20363638, 11333271, 9712843, 10498602, 22897854, 16763549, 17222790 |
| Identification Methods | affinity chromatography technology, pull down, fluorescent resonance energy transfer, x-ray crystallography, coimmunoprecipitation, cross-linking study, biochemical, enzyme linked immunosorbent assay, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | F5_F8_type_C~VEGF_C |
| Common GO terms | GO:0001525 - angiogenesis GO:0001569 - branching involved in blood vessel morphogenesis GO:0001570 - vasculogenesis GO:0001938 - positive regulation of endothelial cell proliferation GO:0002040 - sprouting angiogenesis and 20 others more... |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
