Interactor 1: NRP1 (O14786)
Neuropilin-1 (Vascular endothelial cell growth factor 165 receptor) (CD antigen CD304)
Gene: NRP1

Interactor 2: VGFR1 (P17948)
Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)
Gene: FLT1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 23452854
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains MAM~ig
Common GO terms GO:0001525 - angiogenesis
GO:0005021 - vascular endothelial growth factor receptor activity
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
and 5 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 923
Hs

1 1338
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024