Interactor 1: TNF11 (O14788)
Tumor necrosis factor ligand superfamily member 11 (Osteoclast differentiation factor) (ODF) (Osteoprotegerin ligand) (OPGL) (Receptor activator of nuclear factor kappa-B ligand) (RANKL) (TNF-related activation-induced cytokine) (TRANCE) (CD antigen CD254) [Cleaved into: Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form]
Gene: TNFSF11
Interactor 2: TNR11 (Q9Y6Q6)
Tumor necrosis factor receptor superfamily member 11A (Osteoclast differentiation factor receptor) (ODFR) (Receptor activator of NF-KB) (CD antigen CD265)
Gene: TNFRSF11A
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.66 | 1.00 | 0.812 |
The method score is based on:
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | RANK_CRD_2~TNF, TNF~TNFR_c6 |
Common GO terms | GO:0001503 - ossification GO:0002548 - monocyte chemotaxis GO:0005886 - plasma membrane GO:0030316 - osteoclast differentiation GO:0033209 - tumor necrosis factor-mediated signaling pathway and 7 others more... |
Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024