Protein: VPS5
Vacuolar protein sorting-associated protein 5 (Carboxypeptidase Y-deficient protein 10) (Vacuolar protein-targeting protein 5)

Gene: VPS5
Organism: Saccharomyces cerevisiae S288C
Interactions: 67
UniProt ID: Q92331

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005768 - endosome
GO:0005829 - cytosol
GO:0010008 - endosome membrane
GO:0012505 - endomembrane system

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

748278

VPS17
Vacuolar protein sorting-associated protein 17

17

1

Small-scale

0.986

High

822488

PEP8
Carboxypeptidase Y-deficient protein 8

11

3

Small-scale

0.973

High

1362958

VPS5
Vacuolar protein sorting-associated protein 5

3

19

Small-scale

0.852

High

757399

VPS35
Vacuolar protein sorting-associated protein 35

14

4

Small-scale

0.762

High

803516

VPS29
Vacuolar protein sorting-associated protein 29

9

2

Small-scale

0.749

High

430956

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

2

2

High-throughput

0.621

High

820247

SSB2
Ribosome-associated molecular chaperone SSB2

2

5

High-throughput

0.621

High

871027

SNAPN
Biogenesis of lysosome-related organelles complex 1 subunit SNN1

2

1

Small-scale

0.608

High

1039150

MUK1
Protein MUK1

2

0

Small-scale

0.605

High

733834

VPS10
Vacuolar protein sorting/targeting protein VPS10

2

0

Small-scale

0.588

High

1043589

ANY1
Scramblase ANY1

2

0

High-throughput

0.587

High

863841

ATG27
Autophagy-related protein 27

1

1

High-throughput

0.541

High

1044211

TVP15
Golgi apparatus membrane protein TVP15

1

0

High-throughput

0.518

High

923829

YIF1
Protein transport protein YIF1

1

2

Small-scale

0.501

High

835518

BUB1
Spindle assembly checkpoint serine/threonine-protein kinase BUB1

1

1

Small-scale

0.494

High

722395

XPO1
Exportin-1

1

10

High-throughput

0.489

High

866040

YMR1
Phosphoinositide 3-phosphatase

1

4

High-throughput

0.489

High

758175

CASP
Protein CASP

1

8

High-throughput

0.481

High

817782

TSC11
Target of rapamycin complex 2 subunit TSC11

1

1

High-throughput

0.481

High

1084924

LAS17
Proline-rich protein LAS17

1

7

High-throughput

0.464

High

672752

BPH1
Beige protein homolog 1

1

0

High-throughput

0.458

High

743736

VATD
V-type proton ATPase subunit D

1

1

High-throughput

0.457

High

863371

NMD5
Nonsense-mediated mRNA decay protein 5

1

2

High-throughput

0.457

High

393597

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.445

High

742789

HSP7F
Heat shock protein homolog SSE1

1

5

High-throughput

0.445

High

665867

KPC1
Protein kinase C-like 1

1

5

High-throughput

0.439

High

737069

CDC3
Cell division control protein 3

1

2

High-throughput

0.439

High

777149

BDF1
Bromodomain-containing factor 1

1

6

High-throughput

0.439

High

813878

MBO1
Gamma tubulin complex adapter SPC72

1

1

High-throughput

0.439

High

919286

YG3A
Uncharacterized protein YGR130C

1

1

High-throughput

0.439

High

1025079

NUM1
Nuclear migration protein NUM1

1

2

High-throughput

0.439

High

802611

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.438

High

866182

ENT3
Epsin-3

1

0

High-throughput

0.438

High

1053590

YTH1
mRNA 3'-end-processing protein YTH1

1

0

High-throughput

0.438

High

708667

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

752945

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.437

High

925470

HDA1
Histone deacetylase HDA1

1

2

High-throughput

0.417

High

1048426

RCO1
Transcriptional regulatory protein RCO1

1

3

High-throughput

0.417

High

1059588

SNA4
Protein SNA4

1

0

High-throughput

0.282

High

477658

MYO1
Myosin-1

1

0

High-throughput

0.251

Low

750812

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.251

Low

918783

NNF2
Protein NNF2

1

0

High-throughput

0.251

Low

1046732

SPC24
Kinetochore protein SPC24

1

0

High-throughput

0.251

Low

594665

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.249

Low

779396

CENPA
Histone H3-like centromeric protein CSE4

1

0

High-throughput

0.249

Low

1045076

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.249

Low

149237

FOB1
DNA replication fork-blocking protein FOB1

1

0

High-throughput

0.238

Low

438173

NOT2
General negative regulator of transcription subunit 2

1

0

High-throughput

0.238

Low

602023

CBF1
Centromere-binding protein 1

1

0

High-throughput

0.238

Low

676692

SGF29
SAGA complex subunit SGF29

1

0

High-throughput

0.238

Low

744074

UTR5
Protein UTR5

1

0

High-throughput

0.238

Low

780730

RRP14
Ribosomal RNA-processing protein 14

1

0

High-throughput

0.238

Low

781600

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.238

Low

805585

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

0

High-throughput

0.238

Low

807709

SMF1
Manganese transporter SMF1

1

0

High-throughput

0.238

Low

835098

HAC1
Transcriptional activator HAC1

1

0

High-throughput

0.238

Low

863810

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.238

Low

865393

YJ08
Putative uncharacterized protein YJR038C

1

0

High-throughput

0.238

Low

922978

ALG12
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase

1

0

High-throughput

0.238

Low

1042726

MZM1
Mitochondrial zinc maintenance protein 1, mitochondrial

1

0

High-throughput

0.238

Low

1045144

HPRT
Hypoxanthine-guanine phosphoribosyltransferase

1

0

High-throughput

0.238

Low

1050273

DFG5
Mannan endo-1,6-alpha-mannosidase DFG5

1

0

High-throughput

0.238

Low

1060063

LMO1
ELMO family protein LMO1

1

0

High-throughput

0.238

Low

1084643

RAD59
DNA repair protein RAD59

1

0

High-throughput

0.238

Low

1084740

YD162
Putative uncharacterized protein YDL162C

1

0

High-throughput

0.238

Low

1084989

NKP1
Inner kinetochore subunit NKP1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025