Interactor 1: GDF8 (O14793)
Growth/differentiation factor 8 (GDF-8) (Myostatin)
Gene: MSTN

Interactor 2: FURIN (P09958)
Furin (EC 3.4.21.75) (Dibasic-processing enzyme) (Paired basic amino acid residue-cleaving enzyme) (PACE)
Gene: FURIN

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 0.60 0.602

The method score is based on:

Property Details
Experiments 25543063, 23829672
Identification Methods enzymatic study, protease assay
Interaction Type cleavage reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0007179 - transforming growth factor beta receptor signaling pathway
GO:0008201 - heparin binding
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 375
Hs

1 794
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024