HitPredict

Interactor 1: TXND9 (O14530)
Thioredoxin domain-containing protein 9 (ATP-binding protein associated with cell differentiation) (Protein 1-4)
Gene: TXNDC9

Interactor 2: TBA4A (P68366)
Tubulin alpha-4A chain (EC 3.6.5.-) (Alpha-tubulin 1) (Testis-specific alpha-tubulin) (Tubulin H2-alpha) (Tubulin alpha-1 chain)
Gene: TUBA4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	1.00	0.892

Property	Details
Experiments	34079125, 28514442, 33961781, unassigned3799
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Thioredoxin~Tubulin
Common GO terms	GO:0000226 - microtubule cytoskeleton organization GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 226 Hs			1 448
+	Hs
		155799 TXND9_HUMAN (1-221): 5.29e-59: 187: 100.00		TBA1C_HUMAN (1-448): 0: 725: 96.21
+	Hs
		155749 TXND9_HUMAN (1-221): 5.29e-59: 187: 100.00		TBA1B_HUMAN (1-439): 0: 714: 97.49
+	Hs
		155773 TXND9_HUMAN (1-221): 5.29e-59: 187: 100.00		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	At
		712487 TRXH1_ARATH (71-163): 1.32e-31: 113: 23.71		TBA3_ARATH (1-435): 0: 776: 82.76
+	Hs
		155722 TXND9_HUMAN (1-221): 5.29e-59: 187: 100.00		TBB5_HUMAN (1-439): 0: 696: 40.55
+	Hs
		997130 PDCL3_HUMAN (36-224): 3.08e-40: 139: 21.88		TBA4A_HUMAN (1-448): 0: 723: 100.00
+	Hs
		1259495 PDCL3_HUMAN (36-224): 3.08e-40: 139: 21.88		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	Mm
		997221 THIOM_MOUSE (74-173): 3.5e-34: 121: 25.49		TBA4A_MOUSE (1-448): 0: 723: 100.00