Interactor 1: AIM2 (O14862)
Interferon-inducible protein AIM2 (Absent in melanoma 2)
Gene: AIM2

Interactor 2: E2AK2 (P19525)
Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (P1/eIF-2A protein kinase) (Protein kinase RNA-activated) (PKR) (Protein kinase R) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2) (p68 kinase)
Gene: EIF2AK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 22801494
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0051092 - positive regulation of NF-kappaB transcription factor activity
GO:0051607 - defense response to virus
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 343
Hs

1 551
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024