Protein: ELK4
ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1) (SRF accessory protein 1)

Gene: ELK4
Organism: Homo sapiens
Interactions: 85
UniProt ID: P28324

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

702349

ACAP2
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2

2

2

High-throughput

0.659

High

549287

SRF
Serum response factor

3

6

Small-scale

0.637

High

702319

ELK4
ETS domain-containing protein Elk-4

1

17

High-throughput

0.618

High

123600

MYO1C
Unconventional myosin-Ic

2

3

High-throughput

0.571

High

162476

ANM5
Protein arginine N-methyltransferase 5

2

3

High-throughput

0.571

High

256780

H2B1K
Histone H2B type 1-K

2

12

High-throughput

0.571

High

415367

HSPB1
Heat shock protein beta-1

2

4

High-throughput

0.571

High

418846

H2A1B
Histone H2A type 1-B/E

2

9

High-throughput

0.571

High

502247

H2A1
Histone H2A type 1

2

9

High-throughput

0.571

High

549536

PRPS2
Ribose-phosphate pyrophosphokinase 2

2

5

High-throughput

0.571

High

634000

H2A1D
Histone H2A type 1-D

2

9

High-throughput

0.571

High

702325

ACADV
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial

2

1

High-throughput

0.571

High

702330

H2BFS
Histone H2B type F-S

2

12

High-throughput

0.571

High

702331

H2B1D
Histone H2B type 1-D

2

12

High-throughput

0.571

High

702332

ACTB
Actin, cytoplasmic 1

2

4

High-throughput

0.571

High

702333

PRPS1
Ribose-phosphate pyrophosphokinase 1

2

5

High-throughput

0.571

High

702336

H4
Histone H4

2

3

High-throughput

0.571

High

702338

TRA2B
Transformer-2 protein homolog beta

2

2

High-throughput

0.571

High

702339

ACTG
Actin, cytoplasmic 2

2

4

High-throughput

0.571

High

702340

H31
Histone H3.1

2

12

High-throughput

0.571

High

702342

H33
Histone H3.3

2

12

High-throughput

0.571

High

702344

AKA12
A-kinase anchor protein 12

2

11

High-throughput

0.571

High

702345

PABP4
Polyadenylate-binding protein 4

2

2

High-throughput

0.571

High

702346

ROCK1
Rho-associated protein kinase 1

2

1

High-throughput

0.571

High

702350

SRSF7
Serine/arginine-rich splicing factor 7

2

3

High-throughput

0.571

High

702351

H31T
Histone H3.1t

2

12

High-throughput

0.571

High

702352

H2A2C
Histone H2A type 2-C

2

9

High-throughput

0.571

High

702354

H2B2F
Histone H2B type 2-F

2

12

High-throughput

0.571

High

702355

H2A2A
Histone H2A type 2-A

2

9

High-throughput

0.571

High

702356

H3C
Histone H3.3C

2

12

High-throughput

0.571

High

702358

H32
Histone H3.2

2

12

High-throughput

0.571

High

702359

H2A3
Histone H2A type 3

2

9

High-throughput

0.571

High

702363

H2A1C
Histone H2A type 1-C

2

9

High-throughput

0.571

High

702364

H2B1H
Histone H2B type 1-H

2

12

High-throughput

0.571

High

702365

H2B1A
Histone H2B type 1-A

2

12

High-throughput

0.571

High

702366

H2A1H
Histone H2A type 1-H

2

9

High-throughput

0.571

High

702368

H2B1N
Histone H2B type 1-N

2

12

High-throughput

0.571

High

702369

H2A1J
Histone H2A type 1-J

2

9

High-throughput

0.571

High

702370

H2B1M
Histone H2B type 1-M

2

12

High-throughput

0.571

High

702371

H2B1L
Histone H2B type 1-L

2

12

High-throughput

0.571

High

702373

MEP50
Methylosome protein WDR77

2

9

High-throughput

0.571

High

702375

H2AJ
Histone H2A.J

2

9

High-throughput

0.571

High

702381

BCLF1
Bcl-2-associated transcription factor 1

2

4

High-throughput

0.571

High

702382

LIMA1
LIM domain and actin-binding protein 1

2

1

High-throughput

0.571

High

702384

TR150
Thyroid hormone receptor-associated protein 3

2

5

High-throughput

0.571

High

702385

NS1BP
Influenza virus NS1A-binding protein

2

2

High-throughput

0.571

High

702322

BRCA1
Breast cancer type 1 susceptibility protein

1

6

Small-scale

0.561

High

702361

DOK4
Docking protein 4

1

2

Small-scale

0.561

High

691635

MK03
Mitogen-activated protein kinase 3

1

18

Small-scale

0.550

High

702323

MK08
Mitogen-activated protein kinase 8

1

20

Small-scale

0.550

High

290865

PPM1B
Protein phosphatase 1B

2

0

High-throughput

0.547

High

330417

LC7L3
Luc7-like protein 3

2

0

High-throughput

0.547

High

599699

YBOX3
Y-box-binding protein 3

2

0

High-throughput

0.547

High

702324

CAPZB
F-actin-capping protein subunit beta

2

0

High-throughput

0.547

High

702327

KIF11
Kinesin-like protein KIF11

2

0

High-throughput

0.547

High

702328

CAZA1
F-actin-capping protein subunit alpha-1

2

0

High-throughput

0.547

High

702329

ICLN
Methylosome subunit pICln

2

0

High-throughput

0.547

High

702334

SMD1
Small nuclear ribonucleoprotein Sm D1

2

0

High-throughput

0.547

High

702335

SMD2
Small nuclear ribonucleoprotein Sm D2

2

0

High-throughput

0.547

High

702341

ERH
Enhancer of rudimentary homolog

2

0

High-throughput

0.547

High

702343

OTUD4
OTU domain-containing protein 4

2

0

High-throughput

0.547

High

702357

LARP1
La-related protein 1

2

0

High-throughput

0.547

High

702360

MTMRE
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR14

2

0

High-throughput

0.547

High

702362

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

2

0

High-throughput

0.547

High

702367

MYCBP
c-Myc-binding protein

2

0

High-throughput

0.547

High

702372

TCF25
Ribosome quality control complex subunit TCF25

2

0

High-throughput

0.547

High

702374

RIOK1
Serine/threonine-protein kinase RIO1

2

0

High-throughput

0.547

High

240059

KPRB
Phosphoribosyl pyrophosphate synthase-associated protein 2

2

5

High-throughput

0.521

High

683580

ITA3
Integrin alpha-3

2

1

High-throughput

0.521

High

702326

SERPH
Serpin H1

2

8

High-throughput

0.521

High

702348

KPRA
Phosphoribosyl pyrophosphate synthase-associated protein 1

2

5

High-throughput

0.521

High

702353

ACTBL
Beta-actin-like protein 2

2

4

High-throughput

0.521

High

702383

COR1C
Coronin-1C

2

7

High-throughput

0.521

High

702379

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

1

Small-scale

0.515

High

702320

MK01
Mitogen-activated protein kinase 1

1

18

Small-scale

0.501

High

702376

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

12

High-throughput

0.500

High

142849

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

473805

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

702321

FUS
RNA-binding protein FUS

1

8

High-throughput

0.479

High

702347

CUL4A
Cullin-4A

1

1

High-throughput

0.479

High

702378

GRPE1
GrpE protein homolog 1, mitochondrial

1

6

High-throughput

0.479

High

702337

H2B1C
Histone H2B type 1-C/E/F/G/I

1

12

High-throughput

0.445

High

702377

RM04
Large ribosomal subunit protein uL4m

2

0

High-throughput

0.298

High

702380

RM16
Large ribosomal subunit protein uL16m

2

0

High-throughput

0.298

High


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Last updated: 11Aug2025