Interactor 1: AIM2 (O14862)
Interferon-inducible protein AIM2 (Absent in melanoma 2)
Gene: AIM2
Interactor 2: CASP1 (P29466)
Caspase-1 (CASP-1) (EC 3.4.22.36) (Interleukin-1 beta convertase) (IL-1BC) (Interleukin-1 beta-converting enzyme) (ICE) (IL-1 beta-converting enzyme) (p45) [Cleaved into: Caspase-1 subunit p20; Caspase-1 subunit p10]
Gene: CASP1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.40 | 0.60 | 0.494 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24630722 |
| Identification Methods | pull down, electron microscopy |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0002221 - pattern recognition receptor signaling pathway GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0032731 - positive regulation of interleukin-1 beta production GO:0050729 - positive regulation of inflammatory response and 4 others more... |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
