HitPredict

Interactor 1: IFIT3 (O14879)
Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (CIG49) (ISG-60) (Interferon-induced 60 kDa protein) (IFI-60K) (Interferon-induced protein with tetratricopeptide repeats 4) (IFIT-4) (Retinoic acid-induced gene G protein) (P60) (RIG-G)
Gene: IFIT3

Interactor 2: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.678

Property	Details
Experiments	25416956, 21516116, 25910212
Identification Methods	two hybrid, split luciferase complementation, two hybrid bait and prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 490 Hs			1 285
+	Hs
		157413 IFIT3_HUMAN (1-490): 2.07e-117: 355: 100.00		TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20
+	Hs
		157458 IFIT3_HUMAN (1-490): 2.07e-117: 355: 100.00		Q5VU62_HUMAN (128-285): 1.66e-39: 137: 100.00
+	Hs
		1132652 CTR9_HUMAN (22-254): 2.71e-11: 68.3: 11.67		FKB15_HUMAN (1-284): 5.16e-27: 112: 13.40