Interactor 1: IFIT3 (O14879)
Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (CIG49) (ISG-60) (Interferon-induced 60 kDa protein) (IFI-60K) (Interferon-induced protein with tetratricopeptide repeats 4) (IFIT-4) (Retinoic acid-induced gene G protein) (P60) (RIG-G)
Gene: IFIT3
Interactor 2: IFIT1 (P09914)
Interferon-induced protein with tetratricopeptide repeats 1 (IFIT-1) (Interferon-induced 56 kDa protein) (IFI-56K) (P56)
Gene: IFIT1
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.977 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 30833792, 21642987, 25416956, 16189514, 21516116, 27107012, 31515488 |
| Identification Methods | affinity chromatography technology, two hybrid, pull down, validated two hybrid, two hybrid array, anti tag coimmunoprecipitation, two hybrid prey pooling approach, barcode fusion genetics two hybrid, molecular sieving, two hybrid pooling approach |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | TPR_12~TPR_12, TPR_12~TPR_8, TPR_12~TPR_7, TPR_7~TPR_8, TPR_2~TPR_8, TPR_8~TPR_8 |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0009615 - response to virus GO:0051607 - defense response to virus GO:0140374 - antiviral innate immune response |
| Homologous interactions | 12 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
