Protein: CHAP1
Chromosome alignment-maintaining phosphoprotein 1 (Zinc finger protein 828)

Gene: CHAP1, CHAMP1
Organism: Homo sapiens
Interactions: 143
UniProt ID: Q96JM3

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0000793 - condensed chromosome
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1395225

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

8

1

Small-scale

0.753

High

1097491

CBX3
Chromobox protein homolog 3

7

12

Small-scale

0.747

High

853378

CBX5
Chromobox protein homolog 5

6

12

Small-scale

0.736

High

1014178

CBX1
Chromobox protein homolog 1

6

12

Small-scale

0.735

High

1277212

POGZ
Pogo transposable element with ZNF domain

3

3

High-throughput

0.667

High

1395206

DEFI6
Differentially expressed in FDCP 6 homolog

3

8

High-throughput

0.667

High

1278789

HDGR2
Hepatoma-derived growth factor-related protein 2

3

9

High-throughput

0.662

High

980147

H4
Histone H4

3

7

High-throughput

0.656

High

1384090

ZN428
Zinc finger protein 428

3

0

High-throughput

0.634

High

1213581

PHF19
PHD finger protein 19

2

6

High-throughput

0.628

High

1395208

ZN644
Zinc finger protein 644

2

2

High-throughput

0.611

High

964417

SUMO2
Small ubiquitin-related modifier 2

2

5

High-throughput

0.602

High

1395212

ZN408
Zinc finger protein 408

2

0

High-throughput

0.602

High

1395223

DAXX
Death domain-associated protein 6

2

1

High-throughput

0.601

High

372856

MYC
Myc proto-oncogene protein

2

15

High-throughput

0.584

High

520292

ANDR
Androgen receptor

2

20

High-throughput

0.584

High

558331

XRCC6
X-ray repair cross-complementing protein 6

2

6

High-throughput

0.584

High

998685

H31
Histone H3.1

2

20

High-throughput

0.584

High

1132895

CHD4
Chromodomain-helicase-DNA-binding protein 4

2

9

High-throughput

0.584

High

1314364

SLX4
Structure-specific endonuclease subunit SLX4

2

19

High-throughput

0.584

High

1259423

TBA1A
Tubulin alpha-1A chain

2

7

High-throughput

0.571

High

502092

H2AZ
Histone H2A.Z

1

10

High-throughput

0.536

High

601807

HMGA1
High mobility group protein HMG-I/HMG-Y

1

5

High-throughput

0.536

High

854229

KI67
Proliferation marker protein Ki-67

1

15

High-throughput

0.536

High

1013093

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

1

High-throughput

0.536

High

1134682

NUMA1
Nuclear mitotic apparatus protein 1

1

11

High-throughput

0.536

High

1163137

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.536

High

1219735

ZMYM4
Zinc finger MYM-type protein 4

1

4

High-throughput

0.536

High

1380942

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

1

High-throughput

0.536

High

1395196

ZN641
Zinc finger protein 641

1

2

High-throughput

0.536

High

1395199

SENP7
Sentrin-specific protease 7

1

3

High-throughput

0.536

High

1395203

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

1

High-throughput

0.536

High

1395214

CBX8
Chromobox protein homolog 8

1

13

High-throughput

0.536

High

1395215

EXOS4
Exosome complex component RRP41

1

2

High-throughput

0.536

High

986634

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

5

High-throughput

0.515

High

214234

MCA3
Eukaryotic translation elongation factor 1 epsilon-1

1

0

High-throughput

0.513

High

391406

FRIL
Ferritin light chain

1

0

High-throughput

0.513

High

542162

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

549661

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.513

High

1128671

ZN460
Zinc finger protein 460

1

0

High-throughput

0.513

High

1395216

SOSSC
SOSS complex subunit C

1

0

High-throughput

0.513

High

1109355

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

1

High-throughput

0.501

High

124954

GTPB1
GTP-binding protein 1

1

7

High-throughput

0.489

High

366109

THRB
Prothrombin

1

1

High-throughput

0.489

High

366290

FA10
Coagulation factor X

1

1

High-throughput

0.489

High

387140

TNNC2
Troponin C, skeletal muscle

1

7

High-throughput

0.489

High

1260477

MTSS2
Protein MTSS 2

1

5

High-throughput

0.489

High

1280211

MILR1
Allergin-1

1

4

High-throughput

0.489

High

1295369

GPSM1
G-protein-signaling modulator 1

1

10

High-throughput

0.489

High

1324481

AN36B
Ankyrin repeat domain-containing protein 36B

1

11

High-throughput

0.489

High

1393365

C2AIL
CDKN2AIP N-terminal-like protein

1

1

High-throughput

0.489

High

1395200

C1QT7
Complement C1q tumor necrosis factor-related protein 7

1

6

High-throughput

0.489

High

129333

MEN1
Menin

1

4

High-throughput

0.479

High

157735

CTRO
Citron Rho-interacting kinase

1

6

High-throughput

0.479

High

223256

PRC1
Protein regulator of cytokinesis 1

1

3

High-throughput

0.479

High

242602

PRKN
E3 ubiquitin-protein ligase parkin

1

11

High-throughput

0.479

High

260307

BRD4
Bromodomain-containing protein 4

1

13

High-throughput

0.479

High

294183

CD123
Translation initiation factor eIF2 assembly protein

1

2

High-throughput

0.479

High

340928

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

18

High-throughput

0.479

High

344982

WIZ
Protein Wiz

1

1

High-throughput

0.479

High

355580

NSD2
Histone-lysine N-methyltransferase NSD2

1

20

Small-scale

0.479

High

406511

MYCN
N-myc proto-oncogene protein

1

12

High-throughput

0.479

High

537716

HSP7C
Heat shock cognate 71 kDa protein

1

5

High-throughput

0.479

High

589424

RFA2
Replication protein A 32 kDa subunit

1

8

High-throughput

0.479

High

607006

CEBPB
CCAAT/enhancer-binding protein beta

1

16

High-throughput

0.479

High

696226

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.479

High

697218

APEX1
DNA repair nuclease/redox regulator APEX1

1

1

High-throughput

0.479

High

754940

H2B1B
Histone H2B type 1-B

1

20

High-throughput

0.479

High

768905

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.479

High

791632

SYUA
Alpha-synuclein

1

2

High-throughput

0.479

High

862380

YAP1
Transcriptional coactivator YAP1

1

15

High-throughput

0.479

High

905038

MECP2
Methyl-CpG-binding protein 2

1

8

High-throughput

0.479

High

915475

HMGA2
High mobility group protein HMGI-C

1

1

Small-scale

0.479

High

942826

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

17

High-throughput

0.479

High

981012

H2B1C
Histone H2B type 1-C/E/F/G/I

1

20

High-throughput

0.479

High

1004977

RNF4
E3 ubiquitin-protein ligase RNF4

1

3

High-throughput

0.479

High

1017118

H33
Histone H3.3

1

20

High-throughput

0.479

High

1066444

RBBP4
Histone-binding protein RBBP4

1

17

High-throughput

0.479

High

1094717

CAF1A
Chromatin assembly factor 1 subunit A

1

7

High-throughput

0.479

High

1094797

CAF1B
Chromatin assembly factor 1 subunit B

1

12

High-throughput

0.479

High

1096789

RFA4
Replication protein A 30 kDa subunit

1

8

High-throughput

0.479

High

1100247

TIF1B
Transcription intermediary factor 1-beta

1

16

High-throughput

0.479

High

1106371

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

16

High-throughput

0.479

High

1114007

CUL3
Cullin-3

1

15

High-throughput

0.479

High

1121070

BOP1
Ribosome biogenesis protein BOP1

1

10

Small-scale

0.479

High

1129698

MDC1
Mediator of DNA damage checkpoint protein 1

1

20

High-throughput

0.479

High

1138516

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

5

High-throughput

0.479

High

1140699

KIF14
Kinesin-like protein KIF14

1

9

High-throughput

0.479

High

1141264

BRD3
Bromodomain-containing protein 3

1

20

High-throughput

0.479

High

1212441

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

1

High-throughput

0.479

High

1235074

ADNP2
Activity-dependent neuroprotector homeobox protein 2

1

13

High-throughput

0.479

High

1255091

TRI67
Tripartite motif-containing protein 67

1

16

High-throughput

0.479

High

1276644

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

12

High-throughput

0.479

High

1289539

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

1310107

MGAP
MAX gene-associated protein

1

11

High-throughput

0.479

High

1313338

SMC5
Structural maintenance of chromosomes protein 5

1

7

High-throughput

0.479

High

1332173

SCAI
Protein SCAI

1

1

High-throughput

0.479

High

1338899

NUP43
Nucleoporin Nup43

1

20

High-throughput

0.479

High

1367026

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1385604

DCPS
m7GpppX diphosphatase

1

2

High-throughput

0.479

High

1395195

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

16

High-throughput

0.479

High

1395197

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

1395201

PCGF6
Polycomb group RING finger protein 6

1

14

High-throughput

0.479

High

1395202

MIS12
Protein MIS12 homolog

1

1

High-throughput

0.479

High

1395204

ADNP
Activity-dependent neuroprotector homeobox protein

1

1

High-throughput

0.479

High

1395205

DSN1
Kinetochore-associated protein DSN1 homolog

1

1

High-throughput

0.479

High

1395207

PKHA4
Pleckstrin homology domain-containing family A member 4

1

10

High-throughput

0.479

High

1395210

WDR76
WD repeat-containing protein 76

1

20

High-throughput

0.479

High

1395211

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

14

High-throughput

0.479

High

1395220

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

4

High-throughput

0.479

High

1395221

HECW2
E3 ubiquitin-protein ligase HECW2

1

7

High-throughput

0.479

High

1395222

ZMYM2
Zinc finger MYM-type protein 2

1

4

High-throughput

0.479

High

1395224

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

1395226

XPO7
Exportin-7

1

5

High-throughput

0.479

High

1395227

TRI33
E3 ubiquitin-protein ligase TRIM33

1

14

High-throughput

0.479

High

1204386

SGO1
Shugoshin 1

1

0

High-throughput

0.458

High

1216480

AHDC1
Transcription factor Gibbin

1

0

High-throughput

0.458

High

1240763

PMF1
Polyamine-modulated factor 1

1

0

High-throughput

0.458

High

1292965

AROS
Active regulator of SIRT1

1

0

High-throughput

0.458

High

1394498

NSL1
Kinetochore-associated protein NSL1 homolog

1

0

High-throughput

0.458

High

1395217

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

58902

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

4

High-throughput

0.445

High

430244

JUN
Transcription factor Jun

1

20

High-throughput

0.445

High

1006629

SRPK2
SRSF protein kinase 2

1

14

High-throughput

0.445

High

1311768

HOMEZ
Homeobox and leucine zipper protein Homez

1

20

High-throughput

0.445

High

1335885

RN169
E3 ubiquitin-protein ligase RNF169

1

5

Small-scale

0.445

High

1395209

ZN576
Zinc finger protein 576

1

3

High-throughput

0.445

High

1395213

LN28A
Protein lin-28 homolog A

1

4

High-throughput

0.445

High

1395218

EXOC1
Exocyst complex component 1

1

0

High-throughput

0.438

High

1258070

UBP53
Ubiquitin carboxyl-terminal hydrolase 53

1

3

Small-scale

0.437

High

1315241

CA174
UPF0688 protein C1orf174

1

0

High-throughput

0.426

High

1162002

H31T
Histone H3.1t

1

20

High-throughput

0.408

High

1392709

S39AD
Zinc transporter ZIP13

1

1

High-throughput

0.407

High

1395219

S39A1
Zinc transporter ZIP1

1

1

High-throughput

0.407

High

1358018

TM171
Transmembrane protein 171

3

0

High-throughput

0.347

High

247154

TBCD4
TBC1 domain family member 4

1

0

High-throughput

0.279

Low

387664

APOC3
Apolipoprotein C-III

1

0

High-throughput

0.279

Low

1395198

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.279

Low

1395228

BACE2
Beta-secretase 2

1

0

High-throughput

0.279

Low

1327136

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.249

Low

1332324

CC71L
Coiled-coil domain-containing protein 71L

1

0

High-throughput

0.249

Low

190460

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.232

Low

880810

NRAM1
Natural resistance-associated macrophage protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025