HitPredict

Interactor 1: KLF11 (O14901)
Krueppel-like factor 11 (Transforming growth factor-beta-inducible early growth response protein 2) (TGFB-inducible early growth response protein 2) (TIEG-2)
Gene: KLF11

Interactor 2: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	22318730
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 512 Hs			1 183
+	Hs
		157875 KLF11_HUMAN (1-512): 3.64e-168: 487: 100.00		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		157891 KLF11_HUMAN (1-512): 3.64e-168: 487: 100.00		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Hs
		728565 ZNF93_HUMAN (52-481): 3.63e-127: 385: 12.74		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		157850 KLF11_HUMAN (1-512): 3.64e-168: 487: 100.00		CBX6_HUMAN (21-124): 3.3e-27: 107: 27.78
+	Hs
		1027081 ZN534_HUMAN (103-481): 8.66e-107: 334: 13.01		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1027087 ZN571_HUMAN (53-448): 2.08e-107: 334: 11.71		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1027217 ZN184_HUMAN (103-478): 6.99e-106: 334: 15.48		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1027150 ZN480_HUMAN (62-420): 9.25e-103: 320: 7.90		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		988824 ZN33A_HUMAN (103-451): 1.65e-92: 300: 13.07		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1027000 ZN846_HUMAN (176-510): 3.56e-86: 277: 16.81		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1027027 ZN568_HUMAN (56-354): 2.97e-71: 240: 7.81		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1027128 ZN565_HUMAN (334-504): 1.08e-69: 233: 23.67		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		549158 ZN250_HUMAN (53-349): 2.12e-68: 231: 9.00		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		316135 ZN184_HUMAN (103-478): 6.99e-106: 334: 15.48		CBX6_HUMAN (21-124): 3.3e-27: 107: 27.78
+	Hs
		240839 Z354A_HUMAN (242-510): 8.78e-61: 211: 15.46		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		800402 ZN568_HUMAN (56-354): 2.97e-71: 240: 7.81		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		316021 ZN33B_HUMAN (103-455): 9.56e-94: 303: 14.29		CBX6_HUMAN (21-124): 3.3e-27: 107: 27.78
+	Hs
		316020 ZN33A_HUMAN (103-451): 1.65e-92: 300: 13.07		CBX6_HUMAN (21-124): 3.3e-27: 107: 27.78
+	Hs
		316039 ZKSC8_HUMAN (62-480): 9.63e-74: 245: 17.05		CBX6_HUMAN (21-124): 3.3e-27: 107: 27.78
+	Hs
		315965 ZNF7_HUMAN (124-478): 4.54e-63: 219: 14.58		CBX6_HUMAN (21-124): 3.3e-27: 107: 27.78